Feng Feng, Zhang Yihe, Zhang Xiao, Mu Bin, Qu Wenjie, Wang Peixia
Engineering Research Center of Ministry of Education for Geological Carbon Storage and Low Carbon Utilization of Resources, Beijing Key Laboratory of Materials Utilization of Nonmetallic Minerals and Solid Wastes, National Laboratory of Mineral Materials, School of Materials Science and Technology, China University of Geosciences (Beijing), Beijing100083, China.
Key Laboratory of Clay Mineral Applied Research of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, China.
ACS Omega. 2024 Apr 8;9(16):17760-17783. doi: 10.1021/acsomega.4c00674. eCollection 2024 Apr 23.
Natural nano-minerals (NNMs) are minerals that are derived from nature with a size of less than 100 nm in at least one dimension in size. NNMs have a number of excellent properties due to their unique nanostructure and have been applied in various fields in recent years. They are rising stars in various disciplines, such as materials, biomedicine, and chemistry, taking advantage of their huge surface area, multiple active sites, excellent adsorption capacity, large quantity, low cost, and nontoxicity, etc. To provide a more comprehensive overview of NNMs and the biomedical applications of NNMs-based nanocomposites, this review classifies NNMs into three types by dimension, lists the structure and properties of typical NNMs, and illustrates their biomedical applications. Furthermore, a novel concept of natural nanomineral medical materials (NNMMs) is proposed, focusing on the medical value of NNMs. In addition, this review attempts to address the current challenges and delineate future directions for the advancement of NNMs. With the deepening of biomedical applications, it is believed that NNMMMs will inevitably play an important role in the field of human health and contribute to its promotion.
天然纳米矿物（NNMs）是源自自然界的矿物，其至少在一个尺寸维度上的大小小于100纳米。由于其独特的纳米结构，NNMs具有许多优异的性能，近年来已应用于各个领域。它们凭借巨大的表面积、多个活性位点、出色的吸附能力、数量众多、成本低廉以及无毒等优势，在材料、生物医学和化学等各个学科领域中成为冉冉升起的新星。为了更全面地概述NNMs以及基于NNMs的纳米复合材料的生物医学应用，本综述按维度将NNMs分为三类，列出了典型NNMs的结构和性能，并阐述了它们的生物医学应用。此外，还提出了天然纳米矿物医用材料（NNMMs）这一新颖概念，重点关注NNMs的医学价值。此外，本综述试图应对当前的挑战，并勾勒出NNMs未来发展的方向。随着生物医学应用的不断深入，相信NNMMs将不可避免地在人类健康领域发挥重要作用，并推动其发展。
