Bishara S E, Jakobsen J R, Krause J C, Sosa-Martinez R
Cleft Palate J. 1986 Apr;23(2):116-25.
The purpose of the study is to determine whether the presence of unoperated clefts of the lip and alveolus or cleft lip and palate have similar effects on the dentofacial relationships of individuals with different racial backgrounds. Nineteen individuals from India and eighteen from Mexico with either unoperated unilateral cleft lip and alveolus or unilateral cleft lip and palate were examined cephalometrically and compared to matched normal individuals. The first step in the data analysis was to compare the normal subjects in the Indian and Mexican samples. Because many statistically significant differences were found between the normal groups, each measure for each patient with a cleft was expressed as a percentage of the mean value for the matched normal group. These relative values for the different measures were then entered into analyses of variance to compare the Indian and Mexican groups with clefts. Subgroups with cleft lip and alveolus were analyzed separately from subgroups with cleft lip and palate. Few group comparisons based on the relative measures were statistically significant, thus suggesting that there was a great similarity in the dentofacial relationships of unoperated individuals with the same cleft type. If the present results are further substantiated by future studies, these findings should enable investigators to pool data on unoperated individuals from various sources. Such an approach can lead to a better understanding of the differences between the various cleft types while eliminating the masking effect of surgical or orthodontic treatment.
本研究的目的是确定未手术的唇腭裂或唇腭裂对不同种族背景个体的牙颌面关系是否有相似影响。对19名来自印度和18名来自墨西哥的患有未手术的单侧唇腭裂或单侧唇腭裂的个体进行了头影测量,并与匹配的正常个体进行比较。数据分析的第一步是比较印度和墨西哥样本中的正常受试者。由于在正常组之间发现了许多具有统计学意义的差异,因此将每名腭裂患者的每项测量值表示为匹配正常组平均值的百分比。然后将这些不同测量值的相对值进行方差分析,以比较有腭裂的印度和墨西哥组。唇腭裂亚组与唇腭裂亚组分别进行分析。基于相对测量值的组间比较很少有统计学意义,因此表明相同腭裂类型的未手术个体的牙颌面关系有很大相似性。如果目前的结果能在未来的研究中得到进一步证实,这些发现将使研究人员能够汇总来自不同来源的未手术个体的数据。这种方法可以更好地理解不同腭裂类型之间的差异,同时消除手术或正畸治疗的掩盖效应。