Faculty of Chemistry, Warsaw University of Technology, Noakowskiego 3, PL-00-664 Warsaw, Poland.
Faculty of Chemistry, University of Warsaw, Pasteura 1, PL-02-093 Warsaw, Poland.
Molecules. 2021 Sep 8;26(18):5464. doi: 10.3390/molecules26185464.
The review covers the chemistry of organoboron heterocycles structurally related to benzoxaboroles where one of the carbon atoms in a boracycle or a fused benzene ring is replaced by a heteroelement such as boron, silicon, tin, nitrogen, phosphorus, or iodine. Related ring expanded systems including those based on naphthalene and biphenyl cores are also described. The information on synthetic methodology as well as the basic structural and physicochemical characteristics of these emerging heterocycles is complemented by a presentation of their potential applications in organic synthesis and medicinal chemistry, the latter aspect being mostly focused on the promising antimicrobial activity of selected compounds.
该综述涵盖了与苯并氧杂硼环结构相关的有机硼杂环化合物的化学性质，其中硼杂环或稠合苯环中的一个碳原子被杂原子如硼、硅、锡、氮、磷或碘取代。还描述了相关的环扩展示例，包括基于萘和联苯核心的体系。关于合成方法的信息以及这些新兴杂环的基本结构和物理化学特性，辅以它们在有机合成和药物化学中的潜在应用的介绍，后者主要集中在选定化合物有希望的抗菌活性上。
