Zarei Moein, El Fray Miroslawa
Department of Polymer and Biomaterials Science, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology inSzczecin, Al. Piastow 45, 71-311 Szczecin, Poland.
Polymers (Basel). 2021 Sep 18;13(18):3177. doi: 10.3390/polym13183177.
Polymeric materials have numerous applications from the industrial to medical fields because of their vast controllable properties. In this study, we aimed to synthesize series of poly(butylene succinate-dilinoleic succinate-ethylene glycol succinate) (PBS-DLS-PEG) copolymers, by two-step polycondensation using a heterogeneous catalyst and a two-step process. PEG of different molecular weights, namely, 1000 g/mol and 6000 g/mol, was used in order to study its effect on the surface and thermal properties. The amount of the PBS hard segment in all copolymers was fixed at 70 wt%, while different ratios between the soft segments (DLS and PEG) were applied. The chemical structure of PBS-DLS-PEG was evaluated using Fourier transform infrared spectroscopy and nuclear magnetic resonance spectroscopy. Gel permeation chromatography was used to determine the molecular weight and dispersity index. The results of structural analysis indicate the incorporation of PEG in the macrochain. The physical and thermal properties of the newly synthesized copolymers were also evaluated using water contact angle measurements, differential scanning calorimetry and dynamic thermomechanical analysis. It was found that increasing the amount of PEG of a higher molecular weight increased the surface wettability of the new materials while maintaining their thermal properties. Importantly, the two-step melt polycondensation allowed a direct fabrication of a polymeric filament with a well-controlled diameter directly from the reactor. The obtained results clearly show that the use of two-step polycondensation in the melt allows obtaining novel PBS-DLS-PEG copolymers and creates new opportunities for the controlled processing of these hydrophilic and thermally stable copolymers for 3D printing technology, which is increasingly used in medical techniques.
由于聚合物材料具有众多可调控的特性，因此在从工业到医疗等诸多领域都有广泛应用。在本研究中，我们旨在通过使用非均相催化剂的两步缩聚反应和两步法合成一系列聚（丁二酸丁二醇酯 - 二亚油酸丁二醇酯 - 乙二醇丁二酸酯）（PBS - DLS - PEG）共聚物。使用不同分子量（即1000 g/mol和6000 g/mol）的聚乙二醇（PEG）来研究其对表面和热性能的影响。所有共聚物中PBS硬段的含量固定为70 wt%，同时应用软段（DLS和PEG）之间的不同比例。使用傅里叶变换红外光谱和核磁共振光谱对PBS - DLS - PEG的化学结构进行了评估。凝胶渗透色谱法用于测定分子量和分散指数。结构分析结果表明PEG已并入大分子链中。还使用水接触角测量、差示扫描量热法和动态热机械分析对新合成共聚物的物理和热性能进行了评估。发现增加较高分子量PEG的用量可提高新材料的表面润湿性，同时保持其热性能。重要的是，两步熔融缩聚反应能够直接从反应器中制备出直径可控的聚合物长丝。所得结果清楚地表明，在熔融状态下使用两步缩聚反应能够获得新型的PBS - DLS - PEG共聚物，并为这些亲水性和热稳定性共聚物的可控加工创造了新机会，以用于日益应用于医疗技术的3D打印技术。
