Albandar J M, Rise J, Gjermo P, Johansen J R
J Clin Periodontol. 1986 Mar;13(3):195-200. doi: 10.1111/j.1600-051x.1986.tb01459.x.
The "random burst" theory has recently been proposed as an explanation of the pattern of periodontal disease progression. The theory predicts that the progression of bone loss at individual sites is not dependent upon previous bone loss and age. A longitudinal radiographic study was designed to test this hypothesis, and to describe the changes in bone level over 2 years in a group of 180 subjects (18-68 years of age) who were not under systematic periodontal treatment. The results indicated that 94% of the sites did not show significant changes in the alveolar bone level during the observation period. The mean annual bone loss for the total population was 0.11 mm. By regressing longitudinal bone loss upon age, it was shown that the rate of bone loss increased rapidly between 33 and 56 years of age while a different pattern was shown for the age intervals 18-32 and 57-68 years. Also, the rate of bone loss increased with increasing initial bone loss. This was less evident in the oldest age group. It was concluded that the progression of bone loss in the present material is consistent with a "burst" theory. However, the progression did not occur randomly with regard to previous loss of alveolar bone and time.
“随机突发”理论最近被提出，作为牙周病进展模式的一种解释。该理论预测，个体部位骨质流失的进展并不取决于先前的骨质流失情况和年龄。一项纵向影像学研究旨在验证这一假设，并描述一组180名未接受系统性牙周治疗的受试者（年龄在18 - 68岁之间）在2年期间骨水平的变化。结果表明，94%的部位在观察期内牙槽骨水平没有显著变化。总体人群的年均骨质流失为0.11毫米。通过对纵向骨质流失与年龄进行回归分析，结果显示，在33至56岁之间骨质流失速率迅速增加，而在18 - 32岁和57 - 68岁年龄区间则呈现出不同的模式。此外，骨质流失速率随着初始骨质流失的增加而增加。这在最年长的年龄组中不太明显。研究得出结论，本研究材料中骨质流失的进展与“突发”理论一致。然而，这种进展并非随机发生，而是与先前的牙槽骨流失情况和时间有关。
