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用于癌症光动力治疗的酞菁聚合物纳米颗粒递送系统的最新进展

Recent Progress in Phthalocyanine-Polymeric Nanoparticle Delivery Systems for Cancer Photodynamic Therapy.

作者信息

Borzęcka Wioleta, Domiński Adrian, Kowalczuk Marek

机构信息

Centre of Polymer and Carbon Materials, Polish Academy of Sciences, ul. M. Curie-Skłodowskiej 34, 41-819 Zabrze, Poland.

出版信息

Nanomaterials (Basel). 2021 Sep 17;11(9):2426. doi: 10.3390/nano11092426.

Abstract

This perspective article summarizes the last decade's developments in the field of phthalocyanine (Pc)-polymeric nanoparticle (NP) delivery systems for cancer photodynamic therapy (PDT), including studies with at least in vitro data. Moreover, special attention will be paid to the various strategies for enhancing the behavior of Pc-polymeric NPs in PDT, underlining the great potential of this class of nanomaterials as advanced Pcs' nanocarriers for cancer PDT. This review shows that there is still a lot of research to be done, opening the door to new and interesting nanodelivery systems.

摘要

这篇观点文章总结了过去十年间用于癌症光动力疗法(PDT)的酞菁(Pc)-聚合物纳米颗粒(NP)递送系统领域的进展,包括至少有体外数据的研究。此外,将特别关注增强Pc-聚合物纳米颗粒在光动力疗法中性能的各种策略,强调这类纳米材料作为先进酞菁类癌症光动力疗法纳米载体的巨大潜力。这篇综述表明仍有许多研究工作要做,为新型且有趣的纳米递送系统打开了大门。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a81/8469866/c7dc000f1943/nanomaterials-11-02426-sch001.jpg

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