Hellenic Health Foundation, Kaisareias 13 & Alexandroupoleos, 11527 Athens, Greece.
Department of Hygiene Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Mikras Asias 75, 11527 Athens, Greece.
Nutrients. 2021 Sep 1;13(9):3077. doi: 10.3390/nu13093077.
The aim of this study was to evaluate the longitudinal changes in alcohol consumption (total alcohol and types of alcoholic beverages) of the Greek EPIC cohort participants (28,572) during a 17-year period (1994-2011), with alcohol information being recorded repeatedly over time. Descriptive statistics were used to show crude trends in drinking behavior. Mixed-effects models were used to study the consumption of total alcohol, wine, beer and spirits/other alcoholic beverages in relation to birth cohort, socio-demographic, lifestyle and health factors. We observed a decreasing trend of alcohol intake as age increased, consistent for total alcohol consumption and the three types of beverages. Older birth cohorts had lower initial total alcohol consumption (8 vs. 10 g/day) and steeper decline in wine, spirits/other alcoholic beverages and total alcohol consumption compared to younger cohorts. Higher education and smoking at baseline had a positive association with longitudinal total alcohol consumption, up to +30% (vs. low education) and more than +25% (vs. non-smoking) respectively, whereas female gender, obesity, history of heart attack, diabetes, peptic ulcer and high blood pressure at baseline had a negative association of -85%, -25%, -16%, -37%, -22% and -24% respectively. Alcohol consumption changed over age with different trends among the studied subgroups and types of alcohol, suggesting targeted monitoring of alcohol consumption.
本研究旨在评估希腊 EPIC 队列参与者(28572 人)在 17 年期间(1994-2011 年)的饮酒量(总饮酒量和各种酒类)的纵向变化,同时多次记录饮酒信息。描述性统计用于显示饮酒行为的粗略趋势。混合效应模型用于研究总饮酒量、葡萄酒、啤酒和烈酒/其他酒类与出生队列、社会人口统计学、生活方式和健康因素之间的关系。我们观察到,随着年龄的增长,酒精摄入量呈下降趋势,总饮酒量和三种类型的饮料均如此。较老的出生队列初始总酒精摄入量较低(8 克/天 vs. 10 克/天),与年轻队列相比,葡萄酒、烈酒/其他酒类和总酒精摄入量的下降幅度更大。基线时的较高教育程度和吸烟与纵向总饮酒量呈正相关,分别增加了 30%(与低教育程度相比)和 25%以上(与不吸烟相比),而基线时的女性、肥胖、心脏病发作史、糖尿病、消化性溃疡和高血压与总饮酒量呈负相关,分别减少了 85%、25%、16%、37%、22%和 24%。随着年龄的增长,饮酒量发生了变化,研究中的亚组和酒类类型的趋势也不同,提示需要对饮酒量进行有针对性的监测。