The Effects of Aerobic-Resistance Training and Broccoli Supplementation on Plasma Dectin-1 and Insulin Resistance in Males with Type 2 Diabetes.

BACKGROUND

This study aimed to evaluate the effects of a combination of aerobic-resistance training (CARET) and broccoli supplementation on dectin-1 levels and insulin resistance in men with type 2 diabetes mellitus (T2D).

METHODS

Forty-four males with T2D were randomly allocated to four groups ( = 11 each group): CARET + broccoli supplement (TS), CARET + placebo (TP), control + broccoli supplement (S), and control + placebo (CP). CARET was performed three days per week for 12 weeks. TS and S groups received 10 g of broccoli supplement per day for 12 weeks. All variables were assessed at baseline and 12 weeks.

RESULTS

Plasma dectin-1 levels were decreased in TS and TP groups compared with the CP group ( < 0.05). Cardiometabolic risk factors showed significant reductions in TP and TS groups compared to S and CP groups ( < 0.05).

CONCLUSION

The combination of CARET and broccoli supplementation produced the largest improvements in insulin resistance and dectin-1 and other complications of T2D.