Nemati Morteza, Bozorgtabar Neda, Hoteit Maha, Sadek Zahra, Almaqhawi Abdullah, Rashidy-Pour Ali, Nemati Nematollah, Rashidi Mohammad, Karimi Niloofar, Khademosharie Mitra, Bagheri Reza, Saeidi Ayoub, Kiyumi Maisa Hamed Al, Heinrich Katie M, Zouhal Hassane
Department of Biomechanics and Sports Injuries, Faculty of Physical Education and Sports Sciences, Kharazmi University, Tehran, Iran.
Department of Sport Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran.
Nutr Metab (Lond). 2024 Nov 14;21(1):91. doi: 10.1186/s12986-024-00860-6.
Supplementing with antioxidants may be one of the most efficient means of minimizing oxidative stress during workouts in obese individuals. The aim of this study is to identify the results after twelve weeks of CrossFit workouts combined with Spinach thylakoid extract on the levels of insulin resistance (insulin and Homeostatic Model Assessment of Insulin Resistance [HOMA-IR]), fasting blood sugar (FBS), malondialdehyde (MDA), creatine kinase (CK), lactate dehydrogenase (LDH), total antioxidant capacity (TAC), and superoxide dismutase (SOD), glutathione peroxidase (GPx) in obese males. Sixty-eight males with an average age of 27 ± 8 yrs and a BMI of 32.6 ± 2.6 kg.m were randomly split into four groups each consisting of seventeen individuals. : control group (CG), supplement group (SG), training group (TG), and training + supplement group (TSG). After initial assessments, the two training groups (TG and TSG) started on a 12 weeks of the CrossFit workouts program involving three sessions per week each lasting up to 60 min. Participants in supplement groups ingested 30 min before lunch, 5 gof Spinach thylakoid extract per day or one sachet of raw corn starch in the control group. Baseline and post-intervention measurements were performed 48 h pre- and post-last session, respectively. The findings revealed noteworthy relationships between the exercise groups and timefor TAC, SOD, GPx, MDA, CK, and LDH (p < 0.001, ES: 0.88, 0.88, 0.8, 0.4, 0.7, and 0.7, respectively). In addition, there were statistically significant differences among study groups after attending the intervention program in TAC (ES: 0.88), SOD (ES: 0.92), GPX (ES: 0.85), MDA (ES: 0.5), CK (ES: 0.7) and LDH (ES: 0.8). The effect sizes of insulin (0.77), glucose (0.21), and HOMA-IR (0.44) varied significantly (p < 0.05) among the groups. The results demonstrated that CrossFit workouts for 12 weeks combined with Spinach thylakoid extract in men with obesity may prevent oxidative damage caused by obesity and CrossFit workouts.
补充抗氧化剂可能是将肥胖个体锻炼期间的氧化应激降至最低的最有效方法之一。本研究的目的是确定在肥胖男性中，为期十二周的CrossFit锻炼与菠菜类囊体提取物相结合对胰岛素抵抗水平（胰岛素和胰岛素抵抗稳态模型评估[HOMA-IR]）、空腹血糖（FBS）、丙二醛（MDA）、肌酸激酶（CK）、乳酸脱氢酶（LDH）、总抗氧化能力（TAC）以及超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GPx）的影响。68名平均年龄为27±8岁、体重指数为32.6±2.6kg/m的男性被随机分为四组，每组17人：对照组（CG）、补充剂组（SG）、训练组（TG）和训练+补充剂组（TSG）。在初始评估后，两个训练组（TG和TSG）开始进行为期12周的CrossFit锻炼计划，每周进行三次，每次持续60分钟。补充剂组的参与者在午餐前30分钟摄入，每天5克菠菜类囊体提取物，对照组则摄入一小袋生玉米淀粉。分别在最后一次训练前48小时和训练后进行基线和干预后测量。研究结果显示，运动组与TAC、SOD、GPx、MDA、CK和LDH的时间之间存在显著关系（p<0.001，效应量分别为0.88、0.88、0.8、0.4、0.7和0.7）。此外，在参加干预计划后，各研究组在TAC（效应量：0.88）、SOD（效应量：0.92）、GPX（效应量：0.85）、MDA（效应量：0.5）、CK（效应量：0.7）和LDH（效应量：0.8）方面存在统计学显著差异。胰岛素（0.77）、葡萄糖（0.21）和HOMA-IR（0.44）的效应量在各组之间差异显著（p<0.05）。结果表明，在肥胖男性中，为期12周的CrossFit锻炼与菠菜类囊体提取物相结合可能预防肥胖和CrossFit锻炼引起的氧化损伤。
