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肾移植受者的 COVID-19 疫苗接种。

COVID-19 vaccination in kidney transplant recipients.

机构信息

Department of Nephrology and Transplantation, University Hospitals of Strasbourg, INSERM Unit 1109, Strasbourg, France.

Department of Transplantation Nephrology and Clinical Immunology Hospices Civils de Lyon, Claude Bernard Lyon I University, INSERM Unit 1111, Lyon, France.

出版信息

Nat Rev Nephrol. 2021 Dec;17(12):785-787. doi: 10.1038/s41581-021-00491-7.

Abstract

Kidney transplant recipients receive therapeutic immunosuppression that impairs their immune responses to the COVID-19 mRNA vaccine. For this reason, this vulnerable patient population is insufficiently protected by the standard two-dose COVID-19 vaccination programme and requires a specific follow-up to guide personalization of an intensified vaccination approach.

摘要

肾移植受者接受治疗性免疫抑制,从而损害其对 COVID-19 mRNA 疫苗的免疫反应。出于这个原因,这一脆弱的患者群体不能充分受到标准两剂 COVID-19 疫苗接种方案的保护,需要进行特定的随访,以指导个体化强化疫苗接种方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e7c/8475856/2b8a551a147e/41581_2021_491_Fig1_HTML.jpg

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