Department of Nephrology and Transplantation, University Hospitals of Strasbourg, INSERM Unit 1109, Strasbourg, France.
Department of Transplantation Nephrology and Clinical Immunology Hospices Civils de Lyon, Claude Bernard Lyon I University, INSERM Unit 1111, Lyon, France.
Nat Rev Nephrol. 2021 Dec;17(12):785-787. doi: 10.1038/s41581-021-00491-7.
Kidney transplant recipients receive therapeutic immunosuppression that impairs their immune responses to the COVID-19 mRNA vaccine. For this reason, this vulnerable patient population is insufficiently protected by the standard two-dose COVID-19 vaccination programme and requires a specific follow-up to guide personalization of an intensified vaccination approach.
肾移植受者接受治疗性免疫抑制,从而损害其对 COVID-19 mRNA 疫苗的免疫反应。出于这个原因,这一脆弱的患者群体不能充分受到标准两剂 COVID-19 疫苗接种方案的保护,需要进行特定的随访,以指导个体化强化疫苗接种方法。