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Literature review on COVID-19 vaccine efficacy in the immunocompromised population, and possible implications to future vaccination in kidney transplant patients.关于新冠病毒疫苗在免疫功能低下人群中的有效性以及对肾移植患者未来疫苗接种可能影响的文献综述。
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本文引用的文献

1
B and T Cell Responses after a Third Dose of SARS-CoV-2 Vaccine in Kidney Transplant Recipients.肾移植受者接种第三剂 SARS-CoV-2 疫苗后的 B 和 T 细胞反应。
J Am Soc Nephrol. 2021 Dec 1;32(12):3027-3033. doi: 10.1681/ASN.2021070966.
2
Temporary hold of mycophenolate augments humoral response to SARS-CoV-2 vaccination in patients with rheumatic and musculoskeletal diseases: a case series.霉酚酸临时停药增强风湿性和肌肉骨骼疾病患者对SARS-CoV-2疫苗的体液免疫反应:病例系列
Ann Rheum Dis. 2022 Feb;81(2):293-295. doi: 10.1136/annrheumdis-2021-221252. Epub 2021 Sep 23.
3
Intensity of mycophenolate mofetil treatment is associated with an impaired immune response to SARS-CoV-2 vaccination in kidney transplant recipients.霉酚酸酯治疗强度与肾移植受者对 SARS-CoV-2 疫苗接种的免疫应答受损有关。
Am J Transplant. 2022 Feb;22(2):634-639. doi: 10.1111/ajt.16851. Epub 2021 Nov 1.
4
A third vaccine dose substantially improves humoral and cellular SARS-CoV-2 immunity in renal transplant recipients with primary humoral nonresponse.第三剂疫苗可显著提高原发性体液无反应的肾移植受者的体液和细胞新冠病毒免疫力。
Kidney Int. 2021 Nov;100(5):1135-1136. doi: 10.1016/j.kint.2021.09.001. Epub 2021 Sep 9.
5
Cellular immunity predominates over humoral immunity after homologous and heterologous mRNA and vector-based COVID-19 vaccine regimens in solid organ transplant recipients.在实体器官移植受者中,同源和异源mRNA及载体型新冠疫苗接种方案后,细胞免疫比体液免疫占优势。
Am J Transplant. 2021 Dec;21(12):3990-4002. doi: 10.1111/ajt.16818. Epub 2021 Sep 6.
6
Randomized Trial of a Third Dose of mRNA-1273 Vaccine in Transplant Recipients.移植受者中第三剂mRNA-1273疫苗的随机试验。
N Engl J Med. 2021 Sep 23;385(13):1244-1246. doi: 10.1056/NEJMc2111462. Epub 2021 Aug 11.
7
SARS-CoV-2 Antibody Responses in Infection-Naive or Previously Infected Individuals After 1 and 2 Doses of the BNT162b2 Vaccine.感染前或既往感染者接种 1 剂和 2 剂 BNT162b2 疫苗后的 SARS-CoV-2 抗体反应。
JAMA Netw Open. 2021 Aug 2;4(8):e2119741. doi: 10.1001/jamanetworkopen.2021.19741.
8
Strong antibody response after a first dose of a SARS-CoV-2 mRNA-based vaccine in kidney transplant recipients with a previous history of COVID-19.有新冠病毒疾病既往史的肾移植受者在接种第一剂基于信使核糖核酸的新冠病毒疫苗后产生强烈抗体反应。
Am J Transplant. 2021 Nov;21(11):3808-3810. doi: 10.1111/ajt.16764. Epub 2021 Jul 23.
9
Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients.肾移植受者和透析患者对 SARS-CoV-2 BNT162b2 疫苗的体液免疫受损。
Sci Immunol. 2021 Jun 15;6(60). doi: 10.1126/sciimmunol.abj1031.
10
Impaired humoral and cellular immunity after SARS-CoV-2 BNT162b2 (tozinameran) prime-boost vaccination in kidney transplant recipients.肾移植受者中 SARS-CoV-2 BNT162b2(tozinameran)疫苗加强接种后体液和细胞免疫受损。
J Clin Invest. 2021 Jul 15;131(14). doi: 10.1172/JCI150175.

COVID-19 Vaccination in Kidney Transplant Recipients: An Ounce Pre-Transplant is Worth a Pound Post-Transplant.

作者信息

Chandran Sindhu, Stock Peter G

机构信息

Department of Medicine, University of California, San Francisco.

Department of Surgery, University of California, San Francisco.

出版信息

J Am Soc Nephrol. 2021 Dec 1;32(12):2977-2978. doi: 10.1681/ASN.2021101347.

DOI:10.1681/ASN.2021101347
PMID:36734819
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8638393/
Abstract
摘要