Gustavsberg Primary Care Center, Region Stockholm, Gustavsberg, Sweden.
Akademiskt Primärvårdscentrum, Region Stockholm, Stockholm, Sweden.
PLoS One. 2021 Sep 28;16(9):e0257854. doi: 10.1371/journal.pone.0257854. eCollection 2021.
Most COVID-19 related infections and deaths may occur in healthcare outside hospitals. Here we explored SARS-CoV-2 infections among healthcare workers (HCWs) in this setting.
All healthcare providers in Stockholm, Sweden were asked to recruit HCWs at work for a study of past or present SARS-CoV-2 infections among HCWs. Study participants This study reports the results from 839 HCWs, mostly employees of primary care centers, sampled in June 2020.
SARS-CoV-2 seropositivity was found among 12% (100/839) of HCWs, ranging from 0% to 29% between care units. Seropositivity decreased by age and was highest among HCWs <40 years of age. Within this age group there was 19% (23/120) seropositivity among women and 11% (15/138) among men (p<0.02). Current infection, as measured using PCR, was found in only 1% and the typical testing pattern of pre-symptomatic potential "superspreaders" found in only 2/839 subjects.
Previous SARS-CoV-2 infections were common among younger HCWs in this setting. Pre-symptomatic infection was uncommon, in line with the strong variability in SARS-CoV-2 exposure between units. Prioritizing infection prevention and control including sufficient and adequate personal protective equipment, and vaccination for all HCWs are important to prevent nosocomial infections and infections as occupational injuries during an ongoing pandemic.
大多数与 COVID-19 相关的感染和死亡可能发生在医院以外的医疗机构。在此，我们探讨了这一环境中卫生保健工作者（HCWs）的 SARS-CoV-2 感染情况。
要求瑞典斯德哥尔摩的所有医疗保健提供者在工作中招募 HCWs，以研究 HCWs 过去或现在的 SARS-CoV-2 感染情况。研究参与者：本研究报告了 2020 年 6 月采样的 839 名 HCWs 的结果，这些 HCWs 主要是初级保健中心的雇员。
在 839 名 HCWs 中，有 12%（100/839）的 HCWs 血清呈阳性，各护理单元之间的血清阳性率从 0%到 29%不等。血清阳性率随年龄下降，在<40 岁的 HCWs 中最高。在这个年龄组中，有 19%（23/120）的女性和 11%（15/138）的男性血清呈阳性（p<0.02）。仅发现 1%的人存在当前感染（通过 PCR 测量），仅在 839 名受试者中的 2 名中发现了典型的有症状前潜在“超级传播者”的检测模式。
在这一环境中，年轻的 HCWs 中以前的 SARS-CoV-2 感染很常见。无症状感染并不常见，这与单位之间 SARS-CoV-2 暴露的强烈变异性一致。优先考虑感染预防和控制措施，包括为所有 HCWs 提供充足和适当的个人防护设备以及接种疫苗，对于防止医院感染和职业性伤害感染至关重要，因为在持续的大流行期间，感染可能会发生。
