Moon R E, Bergquist L V, Conklin B, Miller J N
Chest. 1986 Jun;89(6):846-51. doi: 10.1378/chest.89.6.846.
The Monaghan 225 ventilator was tested to ambient pressures of 6 atmospheres absolute (ATA) in a hyperbaric chamber. The ventilator would function with delivered tidal volume which was independent of ambient pressure. Ventilatory rate declined in an exponential fashion. At 6 ATA, the ventilatory rate was 45 percent of the preset rate at 1 ATA. By decreasing the circuit resistance and increasing the inspiratory flow rate, the 6 ATA rate could be increased to 72 percent of the 1 ATA value. The maximum minute ventilation of the ventilator at 1 ATA was approximately 48 L/min; at 6 ATA, its maximum was 18 L/min. Synchronized intermittent mandatory ventilation, assist/control, and PEEP functions were satisfactory at 6 ATA. While using 100 percent O2 to power the ventilator at 2.82 ATA, the oxygen leakage was 57.7 L/min (converted to 1 ATA pressure, 20 degrees C), of which 33.7 L/min was successfully scavenged using simple techniques. A minor modification was made to the ventilator, allowing it to be driven by compressed air while maintaining complete flexibility in setting the FIo2. The ventilator has proven stable and reliable in clinical use at ambient pressures up to 6 ATA.
莫纳根225型呼吸机在高压舱中进行了至6个绝对大气压(ATA)环境压力的测试。该呼吸机在输送潮气量时能够正常运行,且潮气量与环境压力无关。通气频率呈指数下降。在6 ATA时,通气频率为1 ATA时预设频率的45%。通过降低回路阻力并提高吸气流量,6 ATA时的通气频率可提高至1 ATA时数值的72%。该呼吸机在1 ATA时的最大分钟通气量约为48 L/分钟;在6 ATA时,其最大值为18 L/分钟。同步间歇指令通气、辅助/控制及呼气末正压功能在6 ATA时令人满意。在2.82 ATA使用100%氧气驱动呼吸机时,氧气泄漏量为57.7 L/分钟(换算至1 ATA压力、20摄氏度),其中33.7 L/分钟可通过简单技术成功清除。对呼吸机进行了一项小改动,使其能够由压缩空气驱动,同时在设置吸入氧分数时保持完全灵活性。该呼吸机在高达6 ATA的环境压力下临床使用已证明稳定可靠。