评估脑瘫儿童的微量营养素水平。

Evaluation of micronutrient levels in children with cerebral palsy.

机构信息

Departments of Pediatric Neurology, Eskisehir Osmangazi University, Eskisehir, Turkey.

Department of Pediatric Neurology, Medipol University, Istanbul, Turkey.

出版信息

Pediatr Int. 2022 Jan;64(1):e15005. doi: 10.1111/ped.15005.

DOI:10.1111/ped.15005

PMID:34585809

Abstract

BACKGROUND

Many studies evaluating the nutritional status of children with cerebral palsy (CP) have focused on energy requirements and protein intake. The present work aimed to assess nutritional status and micronutrient levels of children with (CP).

METHODS

This multicenter, cross-sectional and observational study was conducted in 10 different cities in Turkey. Data were available for 398 participants. Anthropometric measurements, feeding mode, nutritional status, and micronutrient levels were evaluated.

RESULTS

The study was conducted with 398 participants (303 patients and 95 healthy controls). Statistical analysis showed that according to the Gomez Classification, weight-for-age (WFA) revealed malnutrition in 92.6% of children with CP, based on Centers for Disease Control and Prevention percentiles. Measurements of micronutrient levels showed that zinc levels were low in patients, whereas vitamin A levels were low in controls. Phosphorous and manganese levels were significantly lower in malnourished children than in typical children. The results revealed that children consuming enteral nutrition solutions had higher selenium and lower zinc levels than non-consumers.

CONCLUSIONS

Malnutrition is not only a protein- or calorie-based problem; micronutrient deficiencies might cause severe health problems. Children with chronic neurological disabilities must be carefully evaluated for these issues. Therefore, nutritional interventions should be adapted to nutrition.

摘要

背景

许多评估脑瘫（CP）儿童营养状况的研究都集中在能量需求和蛋白质摄入上。本研究旨在评估脑瘫儿童的营养状况和微量营养素水平。

方法

这是一项在土耳其 10 个不同城市进行的多中心、横断面和观察性研究。共有 398 名参与者的数据可用。评估了人体测量学测量、喂养方式、营养状况和微量营养素水平。

结果

本研究共纳入 398 名参与者（303 名患者和 95 名健康对照）。统计分析显示，根据 Gomez 分类，根据疾病控制和预防中心百分位数，92.6%的 CP 儿童的体重与年龄比例（WFA）显示存在营养不良。微量营养素水平的测量结果表明，患者的锌水平较低，而对照组的维生素 A 水平较低。与营养良好的儿童相比，营养不良儿童的磷和锰水平显著降低。结果表明，接受肠内营养溶液的儿童的硒水平较高，而锌水平较低，而非接受者的儿童。