多巴胺β-羟化酶水平能否预测双硫仑的不良反应？
Can dopamine beta-hydroxylase levels predict adverse reactions to disulfiram?
作者信息
Ewing J A, Rouse B A, Mueller R A, Silver D
出版信息
Alcohol Clin Exp Res. 1978 Jan;2(1):93-4. doi: 10.1111/j.1530-0277.1978.tb04701.x.
Abstract
Disulfiram had more pronounced sedative effects on healthy normal subjects with low levels of plasma dopamine-beta-hydroxylase (DBH) than it did on subjects with higher levels. It is suggested that DBH levels might provide a means of predicting increased susceptibility to disulfiram side effects.
摘要
与血浆多巴胺-β-羟化酶（DBH）水平较高的受试者相比，双硫仑对血浆DBH水平较低的健康正常受试者具有更明显的镇静作用。有人提出，DBH水平可能提供一种预测双硫仑副作用易感性增加的方法。
Zotero 插件