Ramon y Cajal Health Care Center, Alcorcón, Primary Care Management, Madrid Health Service, Madrid, Spain.
Department of Medical Specialties and Public Health, University Rey Juan Carlos, Alcorcón, Madrid, Spain.
PLoS One. 2021 Sep 29;16(9):e0257546. doi: 10.1371/journal.pone.0257546. eCollection 2021.
To analyze trends in urinary tract infection hospitalization (cystitis, pyelonephritis, prostatitis and non-specified UTI) among patients over 65 years in Spain from 2000-2015.
We conducted a retrospective observational study using the Spanish Hospitalization Minimum Data Set (CMBD), with codifications by the International Classification of Diseases (ICD-9). We collected data on sex, age, type of discharge, main diagnosis, comorbid diagnosis, length of stay, and global cost. All the hospitalizations were grouped by age into three categories: 65-74 years old, 75-84 years old, and 85 years old and above. In the descriptive statistical analysis, crude rates were defined as hospitalizations per 1,000 inhabitants aged ≥65. To identify trends over time, we performed a Joinpoint regression.
From 2000-2015, we found 387,010 hospitalizations coded as UTIs (54,427 pyelonephritis, 15,869 prostatitis, 2643 cystitis and 314,071 non-specified UTI). The crude rate of hospitalization for UTIs between 2000 and 2015 ranged from 2.09 in 2000 to 4.33 in 2015 Rates of hospitalization were higher in men than in women, except with pyelonephritis. By age group, higher rates were observed in patients aged 85 years or older, barring prostatitis-related hospitalizations. Joinpoint analyses showed an average annual percentage increase (AAPC) in incidence rates of 4.9% (95% CI 3.2;6.1) in UTI hospitalizations. We observed two joinpoints, in 2010 and 2013, that found trends of 5.5% between 2000 and 2010 (95% CI 4.7;6.4), 1.5% between 2010 and 2013 (95% CI -6.0;9.6) and 6.8% between 2013 and 2015 (95% CI -0.3;14.4).
The urinary infection-related hospitalization rate in Spain doubled during the period 2000-2015. The highest hospitalization rates occurred in men, in the ≥85 years old age group, and in non-specified UTIs. There were increases in all types of urinary tract infection, with non-specified UTIs having the greatest growth. Understanding these changing trends can be useful for health planning.
分析 2000 年至 2015 年期间西班牙 65 岁以上患者尿路感染住院（膀胱炎、肾盂肾炎、前列腺炎和非特指性尿路感染）的趋势。
我们使用西班牙住院最低数据组（CMBD）进行了回顾性观察性研究，采用国际疾病分类（ICD-9）进行编码。我们收集了性别、年龄、出院类型、主要诊断、合并诊断、住院时间和总费用的数据。所有住院病例按年龄分为三组：65-74 岁、75-84 岁和 85 岁及以上。在描述性统计分析中，粗率定义为每 1000 名≥65 岁居民的住院人数。为了确定随时间的趋势，我们进行了 Joinpoint 回归。
2000 年至 2015 年期间，我们发现了 387010 例尿路感染住院病例（54427 例肾盂肾炎、15869 例前列腺炎、2643 例膀胱炎和 314071 例非特指性尿路感染）。2000 年至 2015 年期间，尿路感染住院的粗率范围为 2.09（2000 年）至 4.33（2015 年）。除了肾盂肾炎外，男性的住院率高于女性。按年龄组划分，85 岁及以上患者的住院率较高，前列腺相关住院率除外。Joinpoint 分析显示，尿路感染住院率的年均百分比变化（AAPC）为 4.9%（95%CI 3.2；6.1）。我们观察到两个连接点，在 2010 年和 2013 年，发现在 2000 年至 2010 年期间，趋势为 5.5%（95%CI 4.7；6.4），在 2010 年至 2013 年期间，趋势为 1.5%（95%CI -6.0；9.6），在 2013 年至 2015 年期间，趋势为 6.8%（95%CI -0.3；14.4）。
2000 年至 2015 年期间，西班牙尿路感染相关住院率翻了一番。最高的住院率发生在男性、≥85 岁年龄组和非特指性 UTIs。所有类型的尿路感染均有所增加，非特指性 UTIs 增长最大。了解这些不断变化的趋势对健康规划很有帮助。
