Division of Women's Health, Research Institute of Traditional Asian Medicine, Kindai University.
Tohoku J Exp Med. 2021 Sep;255(1):71-77. doi: 10.1620/tjem.255.71.
COVID-19 has caused an unprecedented global pandemic. Premenstrual symptoms include mood-related, behavioral, and physical symptoms that are limited to the luteal phase of the menstrual cycle. Psychosocial stress is a risk factor for premenstrual symptoms. The aim of this study was to examine the association between premenstrual symptoms and stress caused by COVID-19. We analyzed data from 871 students with regular menstrual cycles who completed the Premenstrual Symptoms Questionnaire (PSQ), Fear of COVID-19 Scale, and Impact of Event Scale-Revised version (IES-R). The total PSQ score was significantly higher in women with COVID-19-induced posttraumatic stress symptoms (PTSS) than in non-PTSS groups. Compared with pre-pandemic data (2019), the total PSQ score did not change in non-PTSS, but increased in PTSS groups. All symptoms were more severe in PTSS groups than in non-PTSS groups. Compared with 2019, PTSS groups had more severe symptoms for all symptoms except 'physical symptoms' and 'decreased social activity', and non-PTSS groups only exhibited improvements in the 'decreased social activity'. Multiple regression analysis revealed that the IES-R score was a significant exacerbation factor of the total PSQ score, along with age and menstrual pain. This study revealed the association between pandemic-associated PTSS and the severity of premenstrual symptoms.
COVID-19 引发了一场前所未有的全球大流行。经前期症状包括与情绪相关、行为和身体症状，仅限于月经周期的黄体期。心理社会应激是经前期症状的一个危险因素。本研究旨在探讨 COVID-19 引起的经前期症状与应激之间的关系。我们分析了 871 名有规律月经周期的学生的数据，他们完成了经前期症状问卷（PSQ）、COVID-19 恐惧量表和修订后的事件影响量表（IES-R）。与非 PTSD 组相比，COVID-19 所致创伤后应激症状（PTSS）的女性 PSQ 总分明显升高。与大流行前的数据（2019 年）相比，非 PTSD 组的 PSQ 总分没有变化，但 PTSD 组的总分增加。与非 PTSD 组相比，PTSS 组的所有症状都更严重。与 2019 年相比，PTSS 组除了“身体症状”和“社交活动减少”外，所有症状的严重程度都更高，而非 PTSD 组只有“社交活动减少”的症状有所改善。多元回归分析显示，IES-R 评分是 PSQ 总分显著恶化的因素之一，同时还与年龄和月经痛有关。本研究揭示了与大流行相关的 PTSD 与经前期症状严重程度之间的关系。
