• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

An efficient randomised trial design for multi-cancer screening blood tests: nested enhanced mortality outcomes of screening trial.

作者信息

Hackshaw Allan, Berg Christine D

机构信息

Cancer Research UK & UCL Cancer Trials Centre, University College London, London W1T 4TJ, UK.

Division of Cancer Prevention, US National Cancer Institute, Bethesda, MD, USA; medical consultant, Bethesda, MD, USA.

出版信息

Lancet Oncol. 2021 Oct;22(10):1360-1362. doi: 10.1016/S1470-2045(21)00204-7.

DOI:10.1016/S1470-2045(21)00204-7
PMID:34592178
Abstract
摘要

相似文献

1
An efficient randomised trial design for multi-cancer screening blood tests: nested enhanced mortality outcomes of screening trial.一种用于多癌筛查血液检测的高效随机试验设计:筛查试验的嵌套强化死亡率结果
Lancet Oncol. 2021 Oct;22(10):1360-1362. doi: 10.1016/S1470-2045(21)00204-7.
2
Re: All-cause mortality in randomized trials of cancer screening.关于:癌症筛查随机试验中的全因死亡率。
J Natl Cancer Inst. 2002 Jun 5;94(11):864-5; author reply 865-6. doi: 10.1093/jnci/94.11.864.
3
Design of cancer screening trials/randomized trials for evaluation of cancer screening.用于评估癌症筛查的癌症筛查试验/随机试验设计
World J Surg. 2006 Jul;30(7):1152-62. doi: 10.1007/s00268-006-0074-9.
4
Randomized trials of multicancer screening tests: augmenting their ability to identify a genuine mortality benefit.随机多癌筛查试验:提高其识别真正死亡率获益的能力。
J Natl Cancer Inst. 2024 Jul 1;116(7):1005-1007. doi: 10.1093/jnci/djae059.
5
Design of randomized controlled trials to estimate cancer-mortality reductions from multicancer detection screening.用于评估多癌检测筛查降低癌症死亡率的随机对照试验设计。
J Natl Cancer Inst. 2025 Feb 1;117(2):303-311. doi: 10.1093/jnci/djae247.
6
Should we expect all-cause mortality reductions in large screening studies?我们是否应该期待在大型筛查研究中全因死亡率会降低?
Br J Gen Pract. 2018 Jun;68(671):290-291. doi: 10.3399/bjgp18X696545.
7
More efficient, smaller multicancer screening trials.更高效、规模更小的多癌筛查试验。
J Natl Cancer Inst. 2025 Mar 1;117(3):450-455. doi: 10.1093/jnci/djae251.
8
The Need for Randomized Clinical Trials Demonstrating Reduction in All-Cause Mortality With Blood Tests for Cancer Screening.开展随机临床试验以证明癌症筛查血液检测可降低全因死亡率的必要性。
JAMA Intern Med. 2023 Oct 1;183(10):1051-1053. doi: 10.1001/jamainternmed.2023.3610.
9
Multi-cancer early detection tests for general population screening: a systematic literature review.用于普通人群筛查的多癌早期检测测试:一项系统文献综述
Health Technol Assess. 2025 Jan;29(2):1-105. doi: 10.3310/DLMT1294.
10
Transforming the landscape of early cancer detection using blood tests-Commentary on current methodologies and future prospects.利用血液检测改变早期癌症检测格局——述评当前方法学和未来前景。
Br J Cancer. 2021 Apr;124(9):1475-1477. doi: 10.1038/s41416-020-01223-7. Epub 2021 Feb 9.

引用本文的文献

1
Promises and pitfalls of multi-cancer early detection using liquid biopsy tests.使用液体活检检测进行多癌早期检测的前景与陷阱
Nat Rev Clin Oncol. 2025 Jun 13. doi: 10.1038/s41571-025-01033-x.
2
Testing stored control-arm specimens could dramatically increase statistical power yet reduce costs in cancer screening trials.检测储存的对照臂样本可显著提高统计效能,同时降低癌症筛查试验的成本。
J Natl Cancer Inst. 2025 Mar 1;117(3):393-395. doi: 10.1093/jnci/djae293.
3
More efficient, smaller multicancer screening trials.更高效、规模更小的多癌筛查试验。
J Natl Cancer Inst. 2025 Mar 1;117(3):450-455. doi: 10.1093/jnci/djae251.
4
Design of randomized controlled trials to estimate cancer-mortality reductions from multicancer detection screening.用于评估多癌检测筛查降低癌症死亡率的随机对照试验设计。
J Natl Cancer Inst. 2025 Feb 1;117(2):303-311. doi: 10.1093/jnci/djae247.
5
Primary care physicians and laypersons' perceptions of multicancer detection clinical trial designs.初级保健医生和非专业人士对多发性癌症检测临床试验设计的看法。
JNCI Cancer Spectr. 2024 Sep 2;8(5). doi: 10.1093/jncics/pkae084.
6
Increasing power in screening trials by testing control-arm specimens: application to multicancer detection screening.通过检测对照臂样本增加筛查试验的效能:多癌种检测筛查的应用。
J Natl Cancer Inst. 2024 Oct 1;116(10):1675-1682. doi: 10.1093/jnci/djae218.
7
Designing Rigorous and Efficient Clinical Utility Studies for Early Detection Biomarkers.设计严谨高效的早期检测生物标志物临床实用研究。
Cancer Epidemiol Biomarkers Prev. 2024 Sep 3;33(9):1150-1157. doi: 10.1158/1055-9965.EPI-23-1594.
8
Alternative endpoints to mortality in cancer screening trials.癌症筛查试验中死亡率的替代终点。
Mol Oncol. 2024 Aug;18(8):1817-1820. doi: 10.1002/1878-0261.13697. Epub 2024 Jul 6.
9
Increasing power in screening trials by testing control-arm specimens: application to multicancer detection screening.通过检测对照臂样本提高筛查试验效能:在多癌检测筛查中的应用
J Natl Cancer Inst. 2024 Aug 1;116(8):1280-1287. doi: 10.1093/jnci/djae083.
10
Clinical performance and utility: A microsimulation model to inform the design of screening trials for a multi-cancer early detection test.临床性能和实用性:用于为多癌种早期检测试验设计筛选试验提供信息的微模拟模型。
J Med Screen. 2024 Sep;31(3):140-149. doi: 10.1177/09691413241228041. Epub 2024 Feb 2.