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1
Should we expect all-cause mortality reductions in large screening studies?我们是否应该期待在大型筛查研究中全因死亡率会降低？
Br J Gen Pract. 2018 Jun;68(671):290-291. doi: 10.3399/bjgp18X696545.
2
Re: All-cause mortality in randomized trials of cancer screening.关于：癌症筛查随机试验中的全因死亡率。
J Natl Cancer Inst. 2002 Jun 5;94(11):864-5; author reply 865-6. doi: 10.1093/jnci/94.11.864.
3
All-cause mortality in randomized trials of cancer screening.癌症筛查随机试验中的全因死亡率。
J Natl Cancer Inst. 2002 Feb 6;94(3):167-73. doi: 10.1093/jnci/94.3.167.
4
Re: All-cause mortality in randomized trials of cancer screening.关于：癌症筛查随机试验中的全因死亡率
J Natl Cancer Inst. 2002 Jun 5;94(11):862; author reply 865-6. doi: 10.1093/jnci/94.11.862.
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An efficient randomised trial design for multi-cancer screening blood tests: nested enhanced mortality outcomes of screening trial.一种用于多癌筛查血液检测的高效随机试验设计：筛查试验的嵌套强化死亡率结果
Lancet Oncol. 2021 Oct;22(10):1360-1362. doi: 10.1016/S1470-2045(21)00204-7.
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Does screening for disease save lives in asymptomatic adults? Systematic review of meta-analyses and randomized trials.无症状成年人的疾病筛查能否拯救生命？荟萃分析和随机试验的系统评价。
Int J Epidemiol. 2015 Feb;44(1):264-77. doi: 10.1093/ije/dyu140. Epub 2015 Jan 15.
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Screening for cancer: concepts and controversies.癌症筛查：概念与争议
Am Fam Physician. 2014 Nov 1;90(9):625-31.
8
Re: All-cause mortality in randomized trials of cancer screening.关于：癌症筛查随机试验中的全因死亡率。
J Natl Cancer Inst. 2002 Jun 5;94(11):861; author reply 865-6. doi: 10.1093/jnci/94.11.861.
9
Does the source of death information affect cancer screening efficacy results? A study of the use of mortality review versus death certificates in four randomized trials.死亡信息来源是否会影响癌症筛查效果？四项随机试验中使用死亡率审查与死亡证明的比较研究。
Clin Trials. 2010 Feb;7(1):69-77. doi: 10.1177/1740774509356461.
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Screening trials are even more difficult than we thought they were.筛查试验比我们原本想象的还要困难。
J Natl Cancer Inst. 2002 Feb 6;94(3):156-7. doi: 10.1093/jnci/94.3.156.

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Noncancer-Related Mortality in Randomized Clinical Trials: A Meta-Analysis.随机临床试验中的非癌症相关死亡率：一项荟萃分析。
JAMA Netw Open. 2025 Aug 1;8(8):e2526990. doi: 10.1001/jamanetworkopen.2025.26990.
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Avoiding lead-time bias by estimating stage-specific proportions of cancer and non-cancer deaths.通过估计特定阶段癌症和非癌症死亡比例来避免提前期偏倚。
Cancer Causes Control. 2024 May;35(5):849-864. doi: 10.1007/s10552-023-01842-4. Epub 2024 Jan 18.
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Disparity in Lung Cancer Screening Among Smokers and Nonsmokers in China: Prospective Cohort Study.中国烟民与非烟民肺癌筛查率的差异：前瞻性队列研究。
JMIR Public Health Surveill. 2023 Mar 14;9:e43586. doi: 10.2196/43586.
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Cancer-Specific Mortality, All-Cause Mortality, and Overdiagnosis in Lung Cancer Screening Trials: A Meta-Analysis.肺癌筛查试验中的癌症特异性死亡率、全因死亡率和过度诊断：荟萃分析。
Ann Fam Med. 2020 Nov;18(6):545-552. doi: 10.1370/afm.2582.
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An update on CT screening for lung cancer: the first major targeted cancer screening programme.肺癌CT筛查的最新进展：首个主要的针对性癌症筛查项目。
Br J Radiol. 2020 Dec 1;93(1116):20200636. doi: 10.1259/bjr.20200636. Epub 2020 Sep 7.

本文引用的文献

1
Radiation-Induced Breast Cancer Incidence and Mortality From Digital Mammography Screening: A Modeling Study.数字化乳腺钼靶筛查所致辐射诱发的乳腺癌发病率和死亡率：一项建模研究
Ann Intern Med. 2016 Feb 16;164(4):205-14. doi: 10.7326/M15-1241. Epub 2016 Jan 12.
2
Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial.英国卵巢癌筛查协作试验（UKCTOCS）中的卵巢癌筛查与死亡率：一项随机对照试验
Lancet. 2016 Mar 5;387(10022):945-956. doi: 10.1016/S0140-6736(15)01224-6. Epub 2015 Dec 17.
3
Effect of mammographic screening from age 40 years on breast cancer mortality in the UK Age trial at 17 years' follow-up: a randomised controlled trial.17 年随访的英国年龄试验中 40 岁开始的乳腺 X 线筛查对乳腺癌死亡率的影响：一项随机对照试验。
Lancet Oncol. 2015 Sep;16(9):1123-1132. doi: 10.1016/S1470-2045(15)00128-X. Epub 2015 Jul 20.
4
Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up.前列腺癌筛查与死亡率：欧洲前列腺癌筛查随机研究（ERSPC）13年随访结果
Lancet. 2014 Dec 6;384(9959):2027-35. doi: 10.1016/S0140-6736(14)60525-0. Epub 2014 Aug 6.
5
Overdiagnosis in low-dose computed tomography screening for lung cancer.低剂量计算机断层扫描筛查肺癌中的过度诊断。
JAMA Intern Med. 2014 Feb 1;174(2):269-74. doi: 10.1001/jamainternmed.2013.12738.
6
Influence of study features and methods on overdiagnosis estimates in breast and prostate cancer screening.在乳腺癌和前列腺癌筛查中，研究特征和方法对过度诊断估计的影响。
Ann Intern Med. 2013 Jun 4;158(11):831-8. doi: 10.7326/0003-4819-158-11-201306040-00008.
7
Effect of three decades of screening mammography on breast-cancer incidence.三十年来乳腺 X 线筛查对乳腺癌发病率的影响。
N Engl J Med. 2012 Nov 22;367(21):1998-2005. doi: 10.1056/NEJMoa1206809.
8
Should we use total mortality rather than cancer specific mortality to judge cancer screening programmes? Yes.我们应该使用全因死亡率而非癌症特异性死亡率来评判癌症筛查项目吗？答案是肯定的。
BMJ. 2011 Oct 13;343:d6395. doi: 10.1136/bmj.d6395.
9
Reduced lung-cancer mortality with low-dose computed tomographic screening.低剂量计算机断层扫描筛查可降低肺癌死亡率。
N Engl J Med. 2011 Aug 4;365(5):395-409. doi: 10.1056/NEJMoa1102873. Epub 2011 Jun 29.
10
All-cause mortality in randomized trials of cancer screening.癌症筛查随机试验中的全因死亡率。
J Natl Cancer Inst. 2002 Feb 6;94(3):167-73. doi: 10.1093/jnci/94.3.167.

Should we expect all-cause mortality reductions in large screening studies?

作者信息

Dobbin Kevin K, Ebell Mark

机构信息

College of Public Health, University of Georgia, Athens, GA, US.

出版信息

Br J Gen Pract. 2018 Jun;68(671):290-291. doi: 10.3399/bjgp18X696545.

DOI:10.3399/bjgp18X696545
PMID:29853594
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6002009/
Abstract
摘要