肥胖人体测量学指标与埃塞俄比亚北部公职人员高血压的相关性：来自横断面调查的结果。
Association of anthropometric indices of obesity with hypertension among public employees in northern Ethiopia: findings from a cross-sectional survey.
机构信息
Public Health and Health Systems, Nagoya University Graduate School of Medicine Faculty of Medicine, Nagoya, Aichi, Japan.
Health Systems and Population Studies Division, ICDDRB, Dhaka, Bangladesh.
出版信息
BMJ Open. 2021 Sep 30;11(9):e050969. doi: 10.1136/bmjopen-2021-050969.
OBJECTIVES
The burden of hypertension is increasing in low-income countries, including Ethiopia. Obesity is widely known to be associated with hypertension, but different anthropometric indices of obesity might differ in association with hypertension, which is largely unknown in northern Ethiopia.
DESIGN
Data from our previous cross-sectional epidemiological survey were statistically analysed.
SETTING
Public employees in the regional capital city in northern Ethiopia.
PARTICIPANTS
The data of 1380 participants (823 men and 557 non-pregnant women) aged 25 and 64 years were analysed.
OUTCOME MEASURES
The presence of hypertension was the outcome measure and multivariable-adjusted logistic regression analyses were used to investigate the association of body mass index (BMI), waist circumference, and waist-hip ratio in men and women separately. The area under the curve (AUC) for three anthropometric indices for discriminating hypertension was also obtained. Separate analyses were conducted for waist circumference and waist-hip ratio analyses further adjusted for BMI.
RESULTS
BMI was linearly associated with hypertension in men (OR for 1 SD increase in BMI 1.45, p=0.001) and women (OR for 1 SD increase in BMI 1.41, p=0.01). The association of waist circumference was independent of BMI both in men (OR for 1 SD increase in waist circumference: 1.74, p=0.002) and women (OR for 1 SD increase in waist circumference: 1.57, p=0.029). The association of waist-hip ratio with hypertension adjusted for BMI was significant in men (OR for 1 SD increase in the waist-hip ratio: 1.46, p<0.001), but was weak and non-significant in women. The AUC for BMI was 0.64 in men and 0.67 in women, while AUC for waist circumference was 0.69 both in men and women.
CONCLUSIONS
Waist circumference was associated with hypertension independent of BMI among public employees in northern Ethiopia.
目的
在包括埃塞俄比亚在内的低收入国家，高血压的负担正在增加。众所周知，肥胖与高血压密切相关，但不同的肥胖人体测量指标与高血压的相关性可能不同，而这在埃塞俄比亚北部地区还知之甚少。
设计
对我们之前的横断面流行病学调查数据进行了统计分析。
地点
在埃塞俄比亚北部地区首府的公务员中进行。
参与者
对 1380 名年龄在 25 至 64 岁的参与者（823 名男性和 557 名非孕妇）的数据进行了分析。
主要观察指标
高血压的存在是观察结果，使用多变量调整逻辑回归分析分别研究男性和女性的体重指数（BMI）、腰围和腰臀比与高血压的关系。还获得了三种人体测量指标用于区分高血压的曲线下面积（AUC）。对腰围和腰臀比的分析进行了单独分析，并进一步根据 BMI 进行了调整。
结果
BMI 与男性（BMI 每增加 1SD，OR 为 1.45，p=0.001）和女性（BMI 每增加 1SD，OR 为 1.41，p=0.01）的高血压呈线性相关。腰围的相关性与 BMI 无关，无论是在男性（腰围每增加 1SD，OR 为 1.74，p=0.002）还是女性（腰围每增加 1SD，OR 为 1.57，p=0.029）中。在校正 BMI 后，腰臀比与高血压的相关性在男性中具有统计学意义（腰臀比每增加 1SD，OR 为 1.46，p<0.001），但在女性中相关性较弱且无统计学意义。男性的 BMI AUC 为 0.64，女性为 0.67，而男性和女性的腰围 AUC 均为 0.69。
结论
在埃塞俄比亚北部地区的公务员中，腰围与 BMI 无关，与高血压有关。
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