Department of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Kagoshima Kouseiren Hospital, Kagoshima, Japan.
Hypertens Res. 2024 Apr;47(4):867-876. doi: 10.1038/s41440-023-01505-6. Epub 2023 Nov 15.
No existing reports demonstrate the association between anthropometric indices (body mass index, waist circumference, body roundness index, a body shape index) and hypertension according to sex and age in the general Japanese population. This retrospective analysis involved individuals aged 30-69 years who underwent annual medical checkups at Kagoshima Koseiren Hospital in 2005-2019, and who did not meet hypertension criteria at baseline. The outcome was hypertension incidence after 5 years, and its association with baseline anthropometric indices was evaluated using multivariable logistic regression analysis by sex and age. In 41,902 participants (age 52.3 ± 10.2 years, 47.7% men), 7622 individuals (18.2%) developed hypertension after 5 years. Body mass index, waist circumference, and body roundness index were significantly associated with the development of hypertension in both men and women across all age categories from 30 s to 60 s. In the population with a body mass index <25 kg/m, waist circumference and body roundness index were significantly associated with hypertension after 5 years. A body shape index was significantly associated with the development of hypertension in men in their 40 s and 50 s but not in women of any age group. The area under the curve values were lower for a body shape index than for body mass index, waist circumference, and body roundness index in both men and women of all age groups. A body shape index was not a stronger indicator for 5-year hypertension incidence than body mass index, waist circumference, or body roundness index in both men and women across age groups from their 30s-60 s. The results of this study will help to more efficiently identify populations at high risk of developing hypertension and provide preventive interventions. A total of 41,902 participants from health checkup programs were stratified by gender and age to investigate the association between baseline anthropometric indices and hypertension incidence over a 5-year period. BMI, WC, and BRI were almost equally effective and showed a better association with risk of developing hypertension in women and young adults compared to men and old adults. Conversely, ABSI showed no greater association than BMI or WC in any age group in both men and women. ABSI, a body shape index; AUC, area under the curve from receiver operating characteristic curve analysis; BMI, body mass index; BRI, body roundness index; WC, waist circumference.
目前尚无报告显示在日本普通人群中，根据性别和年龄，人体测量指数（体重指数、腰围、体圆指数、身体形状指数）与高血压之间存在关联。本回顾性分析纳入了 2005 年至 2019 年在鹿儿岛 Koseiren 医院接受年度体检、基线时未达到高血压标准的 30-69 岁人群。主要结局为 5 年后高血压的发病率，并使用多变量逻辑回归分析按性别和年龄评估其与基线人体测量指数的关系。在 41902 名参与者（年龄 52.3±10.2 岁，47.7%为男性）中，7622 人（18.2%）在 5 年后发生高血压。体重指数、腰围和体圆指数与所有 30-60 岁年龄段男性和女性的高血压发展均显著相关。在体重指数<25kg/m2的人群中，腰围和体圆指数与 5 年后高血压显著相关。身体形状指数与 40 多岁和 50 多岁男性高血压的发展显著相关，但与任何年龄组的女性无关。在所有年龄组的男性和女性中，身体形状指数的曲线下面积值均低于体重指数、腰围和体圆指数。在 30-60 岁的男性和女性中，身体形状指数与 5 年高血压发生率的相关性并不强于体重指数、腰围或体圆指数。本研究结果将有助于更有效地识别易患高血压的高危人群，并提供预防干预措施。共有 41902 名来自健康检查计划的参与者按性别和年龄分层，以调查 5 年内基线人体测量指数与高血压发病率之间的关系。在女性和年轻成年人中，BMI、WC 和 BRI 与高血压发病风险的相关性几乎相同，且优于男性和老年成年人。相比之下，在男性和女性的任何年龄组中，ABSI 与 BMI 或 WC 相比均无更大的相关性。ABSI，身体形状指数；AUC，来自接收者操作特征曲线分析的曲线下面积；BMI，体重指数；BRI，体圆指数；WC，腰围。
