Suppr超能文献

使用 6 MV FF、6 MVFFF 和 10 MVFFF 光子束的 IBA Razor Nano 室在小射野放射治疗中的特性。

Properties of IBA Razor Nano Chamber in small-field radiation therapy using 6 MV FF, 6 MV FFF, and 10 MV FFF photon beams.

机构信息

Unit of Radiotherapy, Department of Oncology, Tampere University Hospital, Tampere, Finland.

Department of Medical Physics, Medical Imaging Center, Tampere University Hospital, Tampere, Finland.

出版信息

Acta Oncol. 2021 Nov;60(11):1419-1424. doi: 10.1080/0284186X.2021.1979644. Epub 2021 Oct 1.

Abstract

BACKGROUND

Small megavoltage photon fields are increasingly used in modern radiotherapy techniques such as stereotactic radiotherapy. Therefore, it is important to study the reliability of dosimetry in the small-field conditions. The IBA Razor Nano Chamber (Nano chamber) ionization chamber is particularly intended for small-field measurements. In this work, properties of the Nano chamber were studied with both measurements and Monte Carlo (MC) simulations.

MATERIAL AND METHODS

The measurements and MC simulations were performed with 6 MV, 6 MV FFF and 10 MV FFF photon beams from the Varian TrueBeam linear accelerator. The source-to-surface distance was fixed at 100 cm. The measurements and MC simulations included profiles, percentage depth doses (PDD), and output factors (OF) in square jaw-collimated fields. The MC simulations were performed with the EGSnrc software system in a large water phantom.

RESULTS

The measured profiles and PDDs obtained with the Nano chamber were compared against IBA Razor Diode, PTW microDiamond and the PTW Semiflex ionization chamber. These results indicate that the Nano chamber is a high-resolution detector and thus suitable for small field profile measurements down to field sizes 2 × 2 cm and appropriate for the PDD measurements. The field output correction factors and field OFs were determined according to TRS-483 protocol In the 6 MV FF and FFF beams, the determined correction factors were within 1.2% for the field sizes of 1 × 1 cm-3 × 3 cm and the experimental and MC defined field output factors showed good agreement.

CONCLUSION

The Nano chamber with its small cavity volume is a potential detector for the small-field dosimetry. In this study, the properties of this detector were characterized with measurements and MC simulations. The determined correction factors are novel results for the NC in the TrueBeam fields.

摘要

背景

小兆伏光子束在立体定向放射治疗等现代放射治疗技术中越来越多地被使用。因此,研究小场条件下的剂量学可靠性非常重要。IBA Razor Nano 腔(Nano 腔)电离室特别适用于小场测量。在这项工作中,通过测量和蒙特卡罗(MC)模拟研究了 Nano 腔的特性。

材料和方法

使用来自瓦里安 TrueBeam 直线加速器的 6 MV、6 MV FFF 和 10 MV FFF 光子束进行了测量和 MC 模拟。源皮距固定在 100 cm。测量和 MC 模拟包括在方形射野限光筒下的剂量分布、百分深度剂量(PDD)和输出因子(OF)。MC 模拟在大型水模体中使用 EGSnrc 软件系统进行。

结果

用 Nano 腔测量的剂量分布和 PDD 与 IBA Razor 二极管、PTW microDiamond 和 PTW Semiflex 电离室进行了比较。这些结果表明,Nano 腔是一种高分辨率探测器,因此适合小至 2×2 cm 的小射野剂量分布测量,也适合 PDD 测量。根据 TRS-483 协议,确定了 和 。在 6 MV FF 和 FFF 射束中,对于 1×1 cm-3×3 cm 的射野尺寸,确定的修正因子 在 1.2%以内,实验和 MC 定义的射野输出因子 之间具有良好的一致性。

结论

具有小腔体积的 Nano 腔是小场剂量学的潜在探测器。在这项研究中,通过测量和 MC 模拟对该探测器的特性进行了表征。确定的修正因子 是 TrueBeam 场中 NC 的新结果。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验