Laser Cutaneous Cosmetic and Plastic Surgery Unit, Villa Donatello Clinic, Florence, Italy.
Biologist, Florence, Italy.
Photobiomodul Photomed Laser Surg. 2021 Oct;39(10):634-636. doi: 10.1089/photob.2021.0076. Epub 2021 Sep 30.
The study assesses the safety and efficacy of a 675-nm laser source on melasma. Melasma is a frequent acquired skin disease defined by the presence of hyperpigmented macules on the face. Study protocol included up to three sessions of the 675-nm laser. Objective evaluation was assessed by using a 5-point visual analogue pain scale (VAS) (range, 0-4). Treatment tolerance was assessed using the 5-point VAS. A mean 3.1 ± 0.7 improvement was reached according to photographic evaluation by VAS. Patients treated one time showed mean clearance of 3.3 ± 0.76, patients treated two times showed mean clearance of 3.0 ± 0.71, and patients treated three times showed mean clearance of 3.0 ± 1. Pain score mean was 1.2 ± 0.4. The 675-nm laser system seems to be safe and effective even in the treatment of facial melasma in patients with Fitzpatrick phototypes IV to V.
该研究评估了 675nm 激光源治疗黄褐斑的安全性和疗效。黄褐斑是一种常见的后天性皮肤疾病，其特征是面部出现色素沉着斑。研究方案包括最多三次 675nm 激光治疗。采用 5 分视觉模拟疼痛量表（VAS）（范围 0-4）进行客观评估。采用 5 分 VAS 评估治疗耐受性。根据 VAS 摄影评估，平均改善 3.1±0.7。单次治疗的患者平均清除率为 3.3±0.76，两次治疗的患者平均清除率为 3.0±0.71，三次治疗的患者平均清除率为 3.0±1。疼痛评分均值为 1.2±0.4。675nm 激光系统似乎是安全有效的，即使在治疗 FItzpatrick 光型 IV 至 V 型的面部黄褐斑患者中也是如此。
