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B细胞与癌症。

B cells and cancer.

作者信息

Engelhard Victor, Conejo-Garcia Jose R, Ahmed Rafi, Nelson Brad H, Willard-Gallo Karen, Bruno Tullia C, Fridman Wolf H

出版信息

Cancer Cell. 2021 Oct 11;39(10):1293-1296. doi: 10.1016/j.ccell.2021.09.007. Epub 2021 Sep 30.

DOI:10.1016/j.ccell.2021.09.007
PMID:34597591
Abstract

Tumor-infiltrating B cells complement T cell-mediated antitumor immunity. A panel of experts share their views on the complexity of B cells within the tumor microenvironment, the variety of mechanisms by which these cells control tumor growth, their organization in tertiary lymphoid structures, and their association with immunotherapy response.

摘要

肿瘤浸润性B细胞补充T细胞介导的抗肿瘤免疫。一组专家就肿瘤微环境中B细胞的复杂性、这些细胞控制肿瘤生长的多种机制、它们在三级淋巴结构中的组织方式以及它们与免疫治疗反应的关联分享了他们的观点。

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