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关于 Gilles de la Tourette 综合征病因的论述

Remarks on the etiology of Gilles de la Tourette's syndrome.

作者信息

Meyer B C, Rose D

出版信息

J Nerv Ment Dis. 1986 Jul;174(7):387-96. doi: 10.1097/00005053-198607000-00002.

Abstract

Utilizing a case of Tourette's syndrome as an illustration, this paper seeks to refine the problem of causality in medical illness. In contrast to numerous examples reported in the literature, the patient presented in this communication, a 26-year-old man afflicted with tics, convulsive movements, intractable vomiting, and coprolalia, failed to respond favorably to medication, although he showed marked improvement in the course of psychotherapy. Despite rather transparent psychodynamic connections between his life history on the one hand and the nature and vicissitudes of his symptomatology on the other, it cannot be concluded that the psychological factors alone can account for the clinical picture; at best they may be regarded as contributory, as opposed to necessary or sufficient causes, a distinction that may be applied to other conditions as well. This report includes a review of some of the literature on Tourette's syndrome, with special emphasis on the case of Dr. Samuel Johnson, who in retrospect appears to have been a likely victim of that unfortunate malady.

摘要

本文以一例妥瑞氏综合征为例,试图阐明医学疾病中的因果关系问题。与文献中报道的众多案例不同,本病例报告中的患者为一名26岁男性,患有抽搐、惊厥性运动、顽固性呕吐和秽语症,尽管在心理治疗过程中他有明显改善,但对药物治疗反应不佳。尽管一方面他的生活史与另一方面他症状的性质及变化之间存在相当明显的心理动力学联系,但不能得出仅心理因素就能解释临床症状的结论;充其量,它们可能被视为促成因素,而非必要或充分原因,这一区别也可能适用于其他病症。本报告包括对一些关于妥瑞氏综合征文献的综述,特别强调了塞缪尔·约翰逊博士的病例,回顾来看,他似乎是这种不幸疾病的受害者。

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