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2020 年除了 COVID-19 之外,微生物诊断领域还发生了什么?

What happened to microbiological diagnosis in 2020 beyond COVID-19?

机构信息

Emilia Cercenado, Servicio de Microbiología y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Dr Esquerdo 46; 28007 Madrid, Spain.

出版信息

Rev Esp Quimioter. 2021 Sep;34 Suppl 1(Suppl1):2-7. doi: 10.37201/req/s01.01.2021. Epub 2021 Sep 30.

DOI:10.37201/req/s01.01.2021
PMID:34598413
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8683012/
Abstract

The global pandemic of COVID-19 has had negative repercussions on the activities and research in clinical microbiology laboratories other than those related to SARS-CoV-2. Nonetheless, the research activity has also continued in other fields. In this brief review, some of the recent publications related to new diagnostic tests, methods for rapid antimicrobial susceptibility testing and for the detection of resistance genes, new diagnostic technologies, and some aspects related to old and emergent pathogens (Candida auris, Elizabethkingia spp. Streptococcus pyogenes) are summarized.

摘要

全球 COVID-19 大流行对临床微生物学实验室的活动和研究产生了负面影响,但与 SARS-CoV-2 无关的研究仍在继续。在这篇简要的综述中,总结了一些最近有关新诊断检测、快速抗菌药物敏感性检测和耐药基因检测方法、新诊断技术以及一些与老病原体和新出现病原体(耳念珠菌、伊丽莎白菌属、化脓性链球菌)相关的方面的出版物。

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Identification of Candida auris and related species by multiplex PCR based on unique GPI protein-encoding genes.基于独特的糖基磷脂酰肌醇(GPI)蛋白编码基因,通过多重聚合酶链反应(PCR)鉴定耳念珠菌及相关菌种。
Mycoses. 2021 Feb;64(2):194-202. doi: 10.1111/myc.13204. Epub 2020 Nov 13.
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Evaluation of the performance of rapid tests for screening carriers of acquired ESBL-producing Enterobacterales and their impact on turnaround time.评估快速检测在筛查获得性产 ESBL 肠杆菌科细菌携带者方面的性能及其对周转时间的影响。
J Hosp Infect. 2021 Feb;108:19-24. doi: 10.1016/j.jhin.2020.10.013. Epub 2020 Oct 24.
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Evaluation of the Xpert Carba-R NxG Assay for Detection of Carbapenemase Genes in a Global Challenge Set of Pseudomonas aeruginosa Isolates.评估 Xpert Carba-R NxG 检测泛美铜绿假单胞菌分离株碳青霉烯酶基因的全球挑战集。
J Clin Microbiol. 2020 Nov 18;58(12). doi: 10.1128/JCM.01098-20.
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