Jesús Oteo-Iglesias, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
Rev Esp Quimioter. 2021 Sep;34 Suppl 1(Suppl1):12-14. doi: 10.37201/req/s01.03.2021. Epub 2021 Sep 30.
There is an urgent need to control the clinical and public health impact that antibiotic resistance (AR) causes worldwide. Any measure for its control must be based on an up-to-date and comprehensive knowledge of the situation. However, it is difficult to determine the current dimension of AR because a large part of the available information is based on heterogeneous, insufficiently unified and retrospective data. The integration of genomic information in the surveillance of AR is another important factor for improvement. The Spanish Network of Laboratories for the Surveillance of Resistant Microorganisms (RedLabRA) is a structured network of interconnected microbiology laboratories developed within the Spanish National Plan against Antibiotic Resistance. Its main objective is to support the diagnosis of resistance to antibiotics, integrating molecular characterization in the surveillance.
目前急需控制抗生素耐药性(AR)在全球范围内对临床和公共卫生造成的影响。任何控制措施都必须基于对当前情况的最新和全面的了解。然而,由于可用信息的很大一部分基于异质的、不够统一和回顾性的数据,因此很难确定 AR 的当前规模。将基因组信息整合到 AR 的监测中是另一个重要的改进因素。西班牙耐药微生物监测实验室网络(RedLabRA)是在西班牙国家抗生素耐药性防治计划内建立的相互关联的微生物学实验室的结构化网络。其主要目标是通过整合分子特征来支持对抗生素耐药性的诊断,从而支持对耐药性的监测。