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癌症或肝硬化患者以及新生儿的血清对淋巴细胞的皮质醇代谢具有抑制作用。

Sera of patients with cancer or cirrhosis and of newborns exhibiting inhibitory effects on the metabolism of cortisol by lymphocytes.

作者信息

Klein A, Archer S M, Malkin A

出版信息

J Natl Cancer Inst. 1986 Jul;77(1):29-31.

PMID:3459922
Abstract

The effect was examined of ethanol extracts of normal sera (NS), cancer patients' sera (CPS), cirrhosis patients' sera (CirPS), and umbilical cord sera (UCS) on cortisol metabolism by lymphocytes (CML). All the ethanol extracts of these sera showed an inhibitory effect on CML. The most significant inhibition was obtained with CPS and CirPS followed by UCS. A significant inhibition of NS was obtained after doubling their equivalent volume.

摘要

研究了正常血清（NS）、癌症患者血清（CPS）、肝硬化患者血清（CirPS）和脐带血清（UCS）的乙醇提取物对淋巴细胞皮质醇代谢（CML）的影响。这些血清的所有乙醇提取物均对CML有抑制作用。CPS和CirPS的抑制作用最为显著，其次是UCS。NS在其等效体积加倍后也有显著抑制作用。

相似文献

1
Sera of patients with cancer or cirrhosis and of newborns exhibiting inhibitory effects on the metabolism of cortisol by lymphocytes.癌症或肝硬化患者以及新生儿的血清对淋巴细胞的皮质醇代谢具有抑制作用。
J Natl Cancer Inst. 1986 Jul;77(1):29-31.
2
Effect of ethanol extract of cancer patients' serum on the vulnerability of lymphocytes to cortisol.癌症患者血清乙醇提取物对淋巴细胞对皮质醇敏感性的影响。
Tumour Biol. 1988;9(5):233-40. doi: 10.1159/000217567.
3
Albumin and the unique pattern of inhibitors of cortisol catabolism by lymphocytes in serum of cancer patients.白蛋白与癌症患者血清中淋巴细胞对皮质醇分解代谢的独特抑制模式。
Tumour Biol. 1989;10(3):149-52. doi: 10.1159/000217611.
4
Cancer patients' plasma lacking lymphocytic cortisol metabolism-enhancing factor in comparison with plasma of healthy donors.与健康供体的血浆相比，癌症患者的血浆缺乏淋巴细胞皮质醇代谢增强因子。
J Natl Cancer Inst. 1979 May;62(5):1159-61.
5
Detection of cancer in patients by reduced lymphocytic cortisol metabolism-enhancing effect.通过降低淋巴细胞皮质醇代谢增强效应来检测患者是否患癌。
J Natl Cancer Inst. 1980 Nov;65(5):857-61.
6
First isolation step of a plasma factor which enhances lymphocytic cortisol metabolism and which is reduced in cancer patients.一种可增强淋巴细胞皮质醇代谢且在癌症患者中水平降低的血浆因子的首次分离步骤。
Cancer Detect Prev. 1983;6(1-2):107-10.
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[Activity of agglutinin inhibitor of the kujavian pea (Pisum sativum L.) in mothers' blood and umbilical cord blood considering the course of pregnancy and delivery].[考虑妊娠和分娩过程的库亚维豌豆（Pisum sativum L.）凝集素抑制剂在母体血液和脐带血中的活性]
Ann Acad Med Stetin. 1999;45:41-54.
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Cancer and dysplasia of cervix in relation to reduced lymphocytic cortisol metabolism-enhancing effect.宫颈癌和发育异常与淋巴细胞皮质醇代谢增强作用降低的关系。
J Natl Cancer Inst. 1984 Mar;72(3):605-7.
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Increased responsiveness of the hypothalamus-pituitary-adrenal (HPA) axis to stress in newborns with atopic disposition.具有特应性体质的新生儿下丘脑 - 垂体 - 肾上腺（HPA）轴对应激的反应性增强。
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Increased cortisol concentrations in the cord blood of newborns whose mothers smoked during pregnancy.孕期吸烟母亲所生新生儿脐带血中皮质醇浓度升高。
J Perinat Med. 2006;34(6):466-70. doi: 10.1515/JPM.2006.091.

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