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经腹腔吻合的结直肠手术后早期拔除尿管的系统评价和荟萃分析。

Systematic review and meta-analysis of early removal of urinary catheter after colorectal surgery with infraperitoneal anastomosis.

机构信息

Department of Digestive Surgery, University Hospital CHU, Clermont-Ferrand, France.

Department of Gynaecology, University Hospital CHU, Clermont-Ferrand, France.

出版信息

Langenbecks Arch Surg. 2022 Feb;407(1):15-23. doi: 10.1007/s00423-021-02342-2. Epub 2021 Oct 2.

Abstract

AIM OF THE STUDY

To review and to analyse the feasibility of using no urinary catheter or a catheter for less than 24 h compared with longer post-operative catheter after colorectal surgery with infraperitoneal dissection.

METHODS

We performed a systematic review and meta-analysis of studies comparing no urinary catheter or a catheter for less than 24 h (early removal, ER) and urinary catheter drainage for 2 days or longer (late removal, LR) after colorectal surgery with infraperitoneal dissection. Primary endpoint was acute urinary retention (AUR) requiring a re-catheterization. Secondary endpoints were urinary tract infection (UTI), overall morbidity and hospital length of stay. Meta-analysis met the PRISMA criteria, with a random model.

RESULTS

Out of 3659 articles found, 82 comparative studies on catheter duration were selected, of which five were in colorectal surgery: three randomized trials, one retrospective and one prospective series. There were 396 ER and 410 LR patients. All had undergone surgery with infraperitoneal dissection. There was no significant difference regarding AUR (OR = 2.09 [95%CI 0.97-4.52]) but significantly less UTI (OR = 0.39 [95%CI 0.22-0.67]) for early urinary catheter removal. The number needed to harm was much higher for AUR than for UTI (23.3 vs. 8).

CONCLUSION

This meta-analysis suggests that, in terms of benefit/risk ratio, in colorectal surgery with infraperitoneal anastomosis, early removal (< 24 h) of the urinary catheter would be beneficial (because of a more frequent UTI after LR than AUR after ER) and would reduce the occurrence of UTI if no AUR risk factors are present. However, these findings should be interpreted with caution because of the low quality of evidence.

摘要

研究目的

回顾和分析在经腹腔下结肠直肠手术后,与留置导尿管超过 24 小时相比,不留置导尿管或留置导尿管少于 24 小时(早期拔除,ER)的可行性,并分析留置导尿管 2 天或更长时间(晚期拔除,LR)的可行性。

方法

我们对经腹腔下结肠直肠手术后不留置导尿管或留置导尿管少于 24 小时(早期拔除,ER)与留置导尿管 2 天或更长时间(晚期拔除,LR)的比较研究进行了系统评价和荟萃分析。主要终点是需要重新置管的急性尿潴留(AUR)。次要终点是尿路感染(UTI)、总发病率和住院时间。荟萃分析符合 PRISMA 标准,并采用随机模型。

结果

在 3659 篇文章中,有 82 篇比较导管留置时间的研究被选中,其中 5 篇是关于结肠直肠手术的:3 项随机试验、1 项回顾性研究和 1 项前瞻性系列研究。ER 组有 396 例患者,LR 组有 410 例患者。所有患者均接受经腹腔下手术。在 AUR 方面,早期拔除导尿管与晚期拔除导尿管无显著差异(OR=2.09 [95%CI 0.97-4.52]),但早期拔除导尿管的 UTI 明显较少(OR=0.39 [95%CI 0.22-0.67])。对于 AUR,需要治疗的人数比 UTI 高得多(23.3 比 8)。

结论

荟萃分析表明,在经腹腔下吻合的结肠直肠手术中,早期(<24 小时)拔除导尿管在获益/风险比方面是有益的(因为 LR 后 UTI 比 ER 后 AUR 更常见),并且如果没有 AUR 风险因素,会降低 UTI 的发生。然而,由于证据质量较低,这些发现应谨慎解释。

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