School of Food Engineering, University of Campinas, São Paulo, Brazil.
Medical, Scientific and Regulatory Affairs - Nestlé Nutrition / Nestlé Brazil Ltda, São Paulo, Brazil.
Food Res Int. 2021 Nov;149:110698. doi: 10.1016/j.foodres.2021.110698. Epub 2021 Sep 3.
Docosahexaenoic acid (DHA, 22:6n-3) is an essential long chain polyunsaturated fatty acid associated with the development of the nervous system that has to be consumed by infants through breast milk or complementary food sources and which consumption is also usually inadequate in preschoolers. In this work, the in vitro bioaccessibility of DHA from two commercial infant formulas (8.9 and 9.1%) and two preschool children milks (6.9 and 7.2%), with similar DHA contents but formulated with different ingredients, was not improved by the presence of egg phospholipids in the product formulation. In addition, the importance of the choice of an age-appropriate in vitro digestion method was demonstrated by comparing the DHA bioaccessibility from the infant formulas by the Infogest 2.0 standardized method and a simulated digestion method specific for infants.
二十二碳六烯酸（DHA，22:6n-3）是一种必需的长链多不饱和脂肪酸，与神经系统的发育有关，婴儿必须通过母乳或补充食物来源来摄取，学龄前儿童的摄入量通常也不足。在这项工作中，两种商业婴儿配方（8.9%和 9.1%）和两种学龄前儿童牛奶（6.9%和 7.2%）中 DHA 的体外生物利用度并没有因产品配方中添加蛋黄磷脂而提高，这两种配方中 DHA 的含量相似，但成分不同。此外，通过比较使用 Infogest 2.0 标准化方法和专门针对婴儿的模拟消化方法对婴儿配方中 DHA 的生物利用度，证明了选择适合年龄的体外消化方法的重要性。
