Walan A
Scand J Gastroenterol Suppl. 1986;118:118-22. doi: 10.3109/00365528609090911.
This paper reviews the results of clinical trials with omeprazole, including UK and Scandinavian multicentre trials. The effect of omeprazole on ulcer healing and symptom relief has been of a magnitude never seen before. The action of the drug has also been so rapid and pronounced that it has not yet been possible to determine the lowest dose which should be recommended to achieve an optimal effect.
本文回顾了奥美拉唑的临床试验结果,包括英国和斯堪的纳维亚的多中心试验。奥美拉唑对溃疡愈合和症状缓解的效果达到了前所未有的程度。该药的作用也非常迅速和显著,以至于尚未确定达到最佳效果应推荐的最低剂量。