Alamri Abdulrahman, Alharbi Khalid, Hassan Khaled, Alhakami Salem, Alosaimi Mohammed, Rofidi Khalid, Ahmed Ibrahim
Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, SAU.
Surgery, Imam Mohammad Ibn Saud Islamic University, Riyadh, SAU.
Cureus. 2021 Aug 28;13(8):e17528. doi: 10.7759/cureus.17528. eCollection 2021 Aug.
Background Diabetic peripheral neuropathy (DPN) is a chronic sensorimotor length-dependent and symmetrical polyneuropathy. Some peripheral neuropathies have painful presentations, and some are painless. DPN can have a potential impact on the patient's life. Objectives This study was conducted in order to investigate the frequency of neuropathic sensory symptoms among patients with uncontrolled diabetes mellitus. Methods This is a cross-sectional study conducted in the Security Forces hospital using the Neuropathy Total Symptom Score-6 (NTSS-6) questionnaire. The questionnaire was administered by contacting patients through the phone. Patients with uncontrolled diabetes (HbA1C >9) were included in the study. Results This study included 285 participants; 58.9% had type II diabetes and 41.1% had type I diabetes, 156 (54.7%) were females, and 129 (45.3%) were males. Most of the patients (51.1%) were 45-64 years old and the majority were non-smokers (77.9%). Patients with neuropathic pain were 182 (63.9%); 79 (43.4%) of them were males and 103 (56.6%) were females. The prevalence of neuropathic symptoms was much higher in females than in males. Conclusion The prevalence of painful DPN is high among patients with long-term uncontrolled diabetes mellitus. Older, unemployed, and low-educated patients are at higher risk of developing painful DPN. Proper glycemic control and lifestyle modifications are essential in preventing the progression of this condition.
背景 糖尿病周围神经病变(DPN)是一种慢性感觉运动性长度依赖性对称性多神经病变。一些周围神经病变有疼痛表现,一些则无疼痛症状。DPN可能对患者生活产生潜在影响。目的 本研究旨在调查糖尿病控制不佳患者中神经病理性感觉症状的发生频率。方法 这是一项在安全部队医院开展的横断面研究,使用神经病变总症状评分-6(NTSS-6)问卷。通过电话联系患者来发放问卷。纳入糖尿病控制不佳(糖化血红蛋白>9)的患者。结果 本研究纳入285名参与者;58.9%患有2型糖尿病,41.1%患有1型糖尿病,156名(54.7%)为女性,129名(45.3%)为男性。大多数患者(51.1%)年龄在45 - 64岁,且大多数为非吸烟者(77.9%)。有神经病理性疼痛的患者为182名(63.9%);其中79名(43.4%)为男性,103名(56.6%)为女性。女性神经病理性症状的患病率远高于男性。结论 在长期糖尿病控制不佳的患者中,疼痛性DPN的患病率较高。年龄较大、失业且受教育程度低的患者发生疼痛性DPN的风险更高。适当的血糖控制和生活方式改变对于预防这种疾病的进展至关重要。