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沙特糖尿病患者的糖尿病周围神经病变:初级卫生保健机构的多中心横断面研究。

Diabetic peripheral neuropathy among Saudi diabetic patients: A multicenter cross-sectional study at primary health care setting.

作者信息

Sendi Rayan Abdullah, Mahrus Amani Mohammed, Saeed Ruba Mohammed, Mohammed Moneer Adnan, Al-Dubai Sami Abdo Radman

机构信息

Joint Program of Family Medicine Post Graduate Studies, Al-Madinah 41311, Saudi Arabia.

Family Medicine Department, Prince Mohammed Ben Abdulaziz Hospital NGHA, Al-Madinah 41311, Saudi Arabia.

出版信息

J Family Med Prim Care. 2020 Jan 28;9(1):197-201. doi: 10.4103/jfmpc.jfmpc_927_19. eCollection 2020 Jan.

DOI:10.4103/jfmpc.jfmpc_927_19
PMID:32110590
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7014898/
Abstract

BACKGROUND

Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes and is responsible for morbidity and disability among diabetic patients.

OBJECTIVES

The aim of this study was to assess the prevalence of painful DPN and its associated risk factors in patients with diabetes mellitus.

MATERIALS AND METHODS

A cross-sectional study was conducted among 430 diabetic patients attending primary healthcare centres (PHC) in AL Madinah city, Saudi Arabia. The validated Douleur Neuropathique-4 (DN4) questionnaire was used to identify the presence of painful DPN.

RESULTS

The majority were female (54.7%) and had type 2 diabetes mellitus (74.9%). The prevalence of DPN was 30.1% in type 2 diabetic patients and 25.9% in type 1 diabetic patients with an overall prevalence of 29.1%. DPN was associated significantly with age, duration of diabetes milieus, uncontrolled A1c, and positive family history of diabetes mellitus ( < 0.05). All the investigated comorbidities were also associated significantly with DPN ( < 0.05).

CONCLUSIONS

The prevalence of DPN was 25.9% and was associated with age duration of DM and uncontrolled HbA1c. PHC physicians treating diabetes should be more aware of the importance of screening for DPN and the treatment plan.

摘要

背景

糖尿病周围神经病变(DPN)是糖尿病最常见的并发症之一,是糖尿病患者发病和致残的原因。

目的

本研究旨在评估糖尿病患者中疼痛性DPN的患病率及其相关危险因素。

材料与方法

在沙特阿拉伯麦地那市的初级医疗保健中心(PHC)对430名糖尿病患者进行了一项横断面研究。使用经过验证的神经病理性疼痛-4(DN4)问卷来确定疼痛性DPN的存在。

结果

大多数为女性(54.7%),患有2型糖尿病(74.9%)。2型糖尿病患者中DPN的患病率为30.1%,1型糖尿病患者中为25.9%,总体患病率为29.1%。DPN与年龄、糖尿病病程、未控制的糖化血红蛋白以及糖尿病家族史显著相关(<0.05)。所有调查的合并症也与DPN显著相关(<0.05)。

结论

DPN的患病率为25.9%,与糖尿病病程和未控制的糖化血红蛋白有关。治疗糖尿病的初级医疗保健中心医生应更加意识到筛查DPN的重要性和治疗方案。

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