Department of Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, MA, United States.
Front Cell Infect Microbiol. 2021 Sep 16;11:735394. doi: 10.3389/fcimb.2021.735394. eCollection 2021.
The COVID-19 pandemic has demonstrated the urgent need to develop vaccine strategies optimized for pregnant people and their newborns, as both populations are at risk of developing severe disease. Although not included in COVID-19 vaccine development trials, pregnant people have had access to these vaccines since their initial release in the US and abroad. The rapid development and distribution of novel COVID-19 vaccines to people at risk, including those who are pregnant and lactating, presents an unprecedented opportunity to further our understanding of vaccine-induced immunity in these populations. In this review, we aim to summarize the literature to date on COVID-19 vaccination in pregnancy and lactation and highlight opportunities for investigation that may inform future maternal vaccine development and implementation strategies.
译文：COVID-19 大流行表明，迫切需要制定针对孕妇及其新生儿的优化疫苗策略，因为这两个群体都有发展为重症的风险。尽管 COVID-19 疫苗开发试验不包括孕妇，但自这些疫苗在美国和其他国家首次推出以来，孕妇已经可以使用这些疫苗。新型 COVID-19 疫苗的快速开发和分发给高危人群，包括孕妇和哺乳期妇女，为进一步了解这些人群中的疫苗诱导免疫提供了前所未有的机会。在这篇综述中，我们旨在总结迄今为止关于妊娠和哺乳期 COVID-19 疫苗接种的文献，并强调可能为未来的母体疫苗开发和实施策略提供信息的调查机会。
