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爱泼斯坦-巴尔病毒相关浆细胞瘤的视网膜表现

Retinal Manifestation of an Epstein-Barr Virus-Associated Plasma Cell Neoplasm.

作者信息

Arslan Eda, Dingerkus Vita Louisa Sophie, Heussen Florian Moritz, Schmidt Adrian, Zaugg Kathrin, Becker Matthias Dieter, Beer Marc

机构信息

Department of Ophthalmology, City Hospital Waid and Triemli, Zurich, Switzerland.

Department of Internal Medicine, Clinic of Medical Oncology and Hematology, City hospital Waid and Triemli, Zurich, Switzerland.

出版信息

Ocul Oncol Pathol. 2021 Sep;7(4):257-261. doi: 10.1159/000514842. Epub 2021 Apr 14.

DOI:10.1159/000514842
PMID:34604197
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8443943/
Abstract

We report a case of an uncommon presentation of Epstein-Barr virus (EBV)-associated plasma cell neoplasm in a patient with a history of prostate cancer and hairy cell leukemia (HCL) in remission after chemotherapy. The diagnosis of an EBV-associated plasma cell neoplasm was challenging as initially the findings were also compatible with a recurrence of HCL. We highlight the value of diagnostic vitrectomy to achieve the diagnosis. Our particular case demonstrates the importance of diagnostic pars plana vitrectomy and aqueous analyses in patients with uveitis of an unknown cause to confirm the diagnosis.

摘要

我们报告了一例罕见的爱泼斯坦-巴尔病毒(EBV)相关浆细胞瘤病例,患者有前列腺癌病史,曾患毛细胞白血病(HCL),化疗后处于缓解期。EBV相关浆细胞瘤的诊断颇具挑战性,因为最初的检查结果也与HCL复发相符。我们强调了诊断性玻璃体切割术对于明确诊断的价值。我们的这个特殊病例表明,对于病因不明的葡萄膜炎患者,诊断性玻璃体切割术及房水分析对于确诊至关重要。

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本文引用的文献

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Epstein-Barr Virus and the Eye.爱泼斯坦-巴尔病毒与眼睛
Ocul Immunol Inflamm. 2020 May 18;28(4):533-537. doi: 10.1080/09273948.2020.1760549.
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Retina. 1999;19(1):45-50. doi: 10.1097/00006982-199901000-00007.
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Unilateral retinal vasculitis associated with hairy cell leukaemia: immunogenetic study.与毛细胞白血病相关的单侧视网膜血管炎:免疫遗传学研究。
Ophthalmologica. 1998;212(5):355-7. doi: 10.1159/000027325.
10
Ocular manifestation of hairy cell leukemia with dramatic response to 2-chloro-deoxy-adenosine.毛细胞白血病的眼部表现对2-氯脱氧腺苷有显著反应。
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