毛细胞白血病的眼部表现对2-氯脱氧腺苷有显著反应。
Ocular manifestation of hairy cell leukemia with dramatic response to 2-chloro-deoxy-adenosine.
作者信息
Robinson A, Eting E, Zeidman A, Djaldetti M, Mittelman M, Savir H
机构信息
Department of Ophthalmology, Golda Medical Center, Hasharon Hospital, Petach-Tikva, Israel.
出版信息
Am J Ophthalmol. 1996 Jan;121(1):97-9. doi: 10.1016/s0002-9394(14)70543-4.
PURPOSE
To demonstrate that hairy cell leukemia may involve the eye.
METHODS
We examined a patient who had a unique ocular manifestation of hairy cell leukemia with severe panuveitis in one eye and leukemic retinopathy in the fellow eye.
RESULTS
Therapy with 2-chloro-deoxy-adenosine, a drug recently introduced for treatment of hairy cell leukemia, led to dramatic improvement of the ocular complications.
CONCLUSIONS
Hairy cell leukemia may involve the eye and ocular symptoms may respond to systemic treatment with 2-chloro-deoxy-adenosine.
目的
证明毛细胞白血病可能累及眼部。
方法
我们检查了一名患有毛细胞白血病独特眼部表现的患者，其一只眼睛有严重全葡萄膜炎，另一只眼睛有白血病性视网膜病变。
结果
使用2-氯脱氧腺苷（一种最近引入用于治疗毛细胞白血病的药物）进行治疗，使眼部并发症得到显著改善。
结论
毛细胞白血病可能累及眼部，眼部症状可能对2-氯脱氧腺苷全身治疗有反应。
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