Singh Saumya, Kola Prithwish, Kaur Dalveer, Singla Gisha, Mishra Vibhu, Panesar Parmjit S, Mallikarjunan Kumar, Krishania Meena
Center of Innovative and Applied Bioprocessing (CIAB), Sector-81 (Knowledge City), Mohali, India.
Food Biotechnology Research Laboratory, Department of Food Engineering & Technology, Sant Longowal Institute of Engineering & Technology Longowal, Longowal, India.
Front Nutr. 2021 Sep 17;8:679312. doi: 10.3389/fnut.2021.679312. eCollection 2021.
Nowadays, despite enormous scientific advances, viral diseases remain the leading cause of morbidity worldwide, and their potential to spread is escalating, eventually turning into pandemics. Nutrition can play a major role in supporting the immune system of the body and for the optimal functioning of the cells of the immune system. A healthy diet encompassing vitamins, multi-nutrient supplements, functional foods, nutraceuticals, and probiotics can play a pivotal role in combating several viral invasions in addition to strengthening the immune system. This review provides comprehensive information on diet-based scientific recommendations, evidence, and worldwide case studies in light of the current pandemic and also with a particular focus on virus-induced respiratory tract infections. After reviewing the immune potential of nutraceuticals based on the lab studies and on human studies, it was concluded that bioactive compounds such as nutraceuticals, vitamins, and functional foods (honey, berries, etc.) with proven antiviral efficacy, in addition to pharmaceutical medication or alone as dietary supplements, can prove instrumental in treating a range of virus-induced infections in addition to strengthening the immune system. Milk proteins and peptides can also act as adjuvants for the design of more potent novel antiviral drugs.
如今,尽管科学取得了巨大进步,但病毒性疾病仍然是全球发病的主要原因,而且它们的传播潜力正在不断升级,最终演变成大流行。营养在支持人体免疫系统以及免疫系统细胞的最佳功能方面可以发挥重要作用。除了增强免疫系统外,包含维生素、多种营养补充剂、功能性食品、营养保健品和益生菌的健康饮食在对抗多种病毒入侵方面可以发挥关键作用。鉴于当前的大流行情况,本综述提供了基于饮食的科学建议、证据以及全球案例研究的全面信息,并且特别关注病毒引起的呼吸道感染。在基于实验室研究和人体研究对营养保健品的免疫潜力进行评估后得出结论,除了药物治疗或单独作为膳食补充剂外,具有已证实抗病毒功效的生物活性化合物,如营养保健品、维生素和功能性食品(蜂蜜、浆果等),除了增强免疫系统外,还可证明有助于治疗一系列病毒引起的感染。乳蛋白和肽也可作为设计更有效新型抗病毒药物的佐剂。