Vezzoni Roberta, Toffoli Ludovica, Conforti Claudio, Dri Arianna, Retrosi Chiara, di Meo Nicola, Magaton Rizzi Giovanni, Signoretto Diego, Zalaudek Iris
Dermatology and Venereology Department, Maggiore Hospital of Trieste, University of Trieste, Trieste, Italy.
Department of Histopathology, Cattinara Hospital of Trieste, Trieste, Italy.
Skin Appendage Disord. 2021 Aug;7(5):339-345. doi: 10.1159/000514566. Epub 2021 May 4.
Neoplastic alopecia (NA) is defined as an organized hair loss in single or multiple areas of the scalp caused by a primary tumor that has metastasized to the skin of the scalp. Due to its localization and clinical appearance, NA should be placed in differential diagnosis with alopecia areata or other entities. To date, pathognomonic dermoscopic criteria of NA have not yet been described: the absence of classical criteria of other scalp diseases in addition to a major neovascularization with on-focus arborizing vessels and erosions or ulcerations may help the clinician to suspect a diagnosis of secondary alopecia. Dermatologists should pay more attention to these rare forms of secondarism because in exceptional cases, a simple alopecia of the scalp can hide a new, relapsing or metastatic neoplasia.
肿瘤性脱发(NA)被定义为由转移至头皮皮肤的原发性肿瘤引起的头皮单处或多处有组织的脱发。由于其定位和临床表现,NA应与斑秃或其他疾病进行鉴别诊断。迄今为止,尚未描述NA的特征性皮肤镜标准:除了主要的新生血管形成伴聚焦性树枝状血管以及糜烂或溃疡外,缺乏其他头皮疾病的经典标准可能有助于临床医生怀疑继发性脱发的诊断。皮肤科医生应更多地关注这些罕见的继发性脱发形式,因为在特殊情况下,单纯的头皮脱发可能隐藏着一种新的、复发性或转移性肿瘤。