Yi Shin, Chen Jia-Syuan, Wang Chang-Ming, Liao Wei-Ssu
Department of Chemistry, National Taiwan University, Taipei 10617, Taiwan.
JACS Au. 2021 Aug 3;1(9):1435-1444. doi: 10.1021/jacsau.1c00202. eCollection 2021 Sep 27.
It is always preferred to perform chemical processes in liquid or gas phases because of the merits of operation convenience, reaction efficiency, and component homogeneity. However, tremendous efforts have to be made to purify the final product and minimize procedure losses unless a well-defined chemical mechanism is found. Herein, an unconventional chemical functioning system accommodating molecule-in-pseudosolid manipulation is reported. It entails the properties of enhanced molecular effective collision and directional guidance for delicate chemical reaction spatial controls. This design achieves facilitated rates on multicomponent chemical reactions with pros of unique simultaneous final product separation through intrapseudosolid spatial limitation. Localized homogeneous component mixing, pronounced molecular collision, and pure product separation happening in this action surmount the obstacles of conventional chemical operation with a straightforward sketch. A path toward fine chemistry is therefore paved, where traditional thoughts on beneficial reaction environments may be reconsidered.
由于操作方便、反应效率高和组分均匀性等优点,在液相或气相中进行化学过程总是更可取的。然而,除非找到明确的化学机制,否则必须付出巨大努力来纯化最终产物并尽量减少过程损失。在此,报道了一种容纳分子在准固体中操纵的非常规化学功能系统。它具有增强分子有效碰撞和定向引导的特性,用于精细的化学反应空间控制。这种设计通过准固体内空间限制实现了独特的同时最终产物分离,从而提高了多组分化学反应的速率。在此过程中发生的局部均匀组分混合、显著的分子碰撞和纯产物分离,以简单的示意图克服了传统化学操作的障碍。因此,为精细化学铺平了道路,在这条道路上,关于有利反应环境的传统观念可能会被重新审视。