穿心莲内酯 F，一种来自爵床科穿心莲属植物的新薁类糖苷。

Centrantheroside F, a new ionone glycoside from .

机构信息

Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education; Yunnan Provincial Center for Research & Development of Natural Products, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.

Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan Minzu University, Kunming 650031, China.

出版信息

J Asian Nat Prod Res. 2022 Aug;24(8):777-783. doi: 10.1080/10286020.2021.1976159. Epub 2021 Oct 4.

DOI:10.1080/10286020.2021.1976159

PMID:34605341

Abstract

One new ionone glycoside, named centrantheroside F (), together with 9 known compounds (-), were isolated from the roots of . Their structures were determined by spectroscopic data analyses and comparing with the literature data. The absolute configuration of was confirmed via 2 D NMR and electronic circular dichroism (ECD). All isolated compounds were evaluated for their inhibitory activity on lipopolysaccharide (LPS)-induced nitric oxide (NO) production.

摘要

从 Centratherum anthelminticum 的根部分离得到一个新的薁酮糖苷，命名为 centrantheroside F ()，以及 9 个已知化合物 (-)。通过光谱数据分析和与文献数据比较确定了它们的结构。通过 2D NMR 和电子圆二色性 (ECD) 确定了的绝对构型。所有分离得到的化合物均进行了 LPS 诱导的一氧化氮 (NO) 产生抑制活性评价。