HPV Cancer Prevention Program, St Jude Children's Research Hospital, Memphis, Tennessee.
University of Utah College of Nursing, Huntsman Cancer Institute, Salt Lake City, Utah.
Cancer. 2022 Jan 15;128(2):237-239. doi: 10.1002/cncr.33920. Epub 2021 Oct 4.
Childhood cancer survivors are at high risk for developing human papillomavirus (HPV)-associated subsequent neoplasms. Henderson et al., 2021 identified risk factors for subsequent HPV-associated malignant neoplasms among enrollees in the Childhood Cancer Survivor Study. The exacerbated risk of subsequent HPV cancers found in the study underscores the need for more stringent surveillance and tracking to inform intervention approaches to ensure maximal protection. In addition, HPV vaccination must be prioritized as part of transitional care and survivorship planning. Limited sources of data on survivor practices and outcomes results in limited information to develop guidelines and provide childhood cancer survivors with information on preventing subsequent HPV cancers. Improved efforts are needed to increase HPV vaccination and HPV-related surveillance among childhood cancer survivors to prevent subsequent neoplasms.
儿童癌症幸存者患人乳头瘤病毒（HPV）相关后续肿瘤的风险很高。Henderson 等人在 2021 年确定了儿童癌症幸存者研究参与者中 HPV 相关恶性肿瘤后续发病的危险因素。研究中发现的 HPV 癌症后续发病风险增加，强调需要更严格的监测和跟踪，以提供干预方法，确保最大程度的保护。此外，HPV 疫苗接种必须作为过渡护理和生存规划的一部分优先考虑。由于幸存者的实践和结果数据有限，因此在制定指南和向儿童癌症幸存者提供有关预防 HPV 相关后续癌症的信息方面，信息有限。需要加强努力，增加儿童癌症幸存者的 HPV 疫苗接种和 HPV 相关监测，以预防后续肿瘤。
