Copplestone J A, Oscier D G, Mufti G J, Hamblin T J
Clin Lab Haematol. 1986;8(2):115-9. doi: 10.1111/j.1365-2257.1986.tb00086.x.
Although leukaemic infiltration of the skin commonly occurs in acute monoblastic leukaemia, the association with chronic myelomonocytic leukaemia (CMML) has only been described recently. We confirm the association and report histologically proven monocytic infiltration of the skin in four patients with CMML. This did not herald a more aggressive phase of the disease as previously suggested. Treatment of the rash with low dose cytarabine or etoposide was effective but razoxane produced no benefit. Superficial radiotherapy was useful to control pruritus in one patient.
尽管皮肤白血病浸润常见于急性单核细胞白血病，但与慢性粒-单核细胞白血病（CMML）的关联直到最近才被描述。我们证实了这种关联，并报告了4例经组织学证实有皮肤单核细胞浸润的CMML患者。这并未预示疾病会进入如之前所认为的更具侵袭性的阶段。用小剂量阿糖胞苷或依托泊苷治疗皮疹有效，但丙亚胺无效。浅表放射治疗对1例患者控制瘙痒有效。
