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患者对鼻窦膜提升和血凝块后恢复的感知与自体骨移植物和脱蛋白猪骨矿物质 1:1 混合物的比较。一项单盲随机对照试验的次要结果。

Patient's perception of recovery after sinus membrane elevation and blood coagulum compared with 1:1 mixture of autogenous bone graft and deproteinized porcine bone mineral. Secondary outcomes from a single-blinded randomized controlled trial.

机构信息

Department of Oral and Maxillofacial Surgery, Aalborg University Hospital and Department of Clinical Medicine, The Faculty of Medicine, Aalborg University, Aalborg, Denmark.

Unit of Clinical Biostatistics, Aalborg University Hospital, Aalborg, Denmark.

出版信息

Clin Oral Implants Res. 2022 Jan;33(1):65-77. doi: 10.1111/clr.13866. Epub 2021 Oct 14.

DOI:10.1111/clr.13866
PMID:34608673
Abstract

OBJECTIVE

The objective was to assess patient's perception of recovery after maxillary sinus membrane elevation (MSME) and blood coagulum (test) compared with maxillary sinus floor augmentation (MSFA) and 1:1 mixture of autogenous bone graft from the buccal antrostomy and deproteinized porcine bone mineral (DPBM) (control).

MATERIALS AND METHODS

Forty healthy patients were randomly allocated to test or control. Oral health-related quality of life (OHRQoL) was evaluated by Oral Health Impact Profile-14 (OHIP-14) at enrollment and 1 week postsurgical. Recovery was estimated by questionnaires and visual analog scale assessing pain, social and working isolation, physical appearance, eating and speaking ability, diet variations, sleep impairment, and discomfort after 1 week and 1 month. Mean differences were expressed with 95% confidence interval (CI). Association between OHRQoL and recovery was estimated. p-value below .05 was considered statistically significant.

RESULTS

Maxillary sinus membrane elevation revealed 2.1 less days of pain (p = .03, 95% CI: 0.2-4.1) and 1.2 days of sick leave (p = .01, 95% CI: 0.3-2.1) compared with MSFA. No significant difference was observed in eating and speaking ability, physical appearance, work performance, and sleep impairment. No significant association between impaired OHRQoL and recovery was observed. Females reported 4.77 higher OHIP-14 score compared with males (p = .01, 95% CI: 1.60-7.94), while association between age and OHIP-14 was -0.10 (p = .28, 95% CI: -0.28 to 0.08).

CONCLUSION

Maxillary sinus membrane elevation revealed significantly less days of pain and sick leave compared with MSFA. Harvesting of autogenous bone graft seems, therefore, to have a significant impact on perception of recovery.

摘要

目的

评估上颌窦膜提升(MSME)和血凝块(测试)与上颌窦底提升(MSFA)和 1:1 自体颊侧窦口骨移植与脱蛋白猪骨矿物质(DPBM)混合物(对照)相比,患者对恢复的感知。

材料和方法

40 名健康患者被随机分配到测试或对照。在入组时和手术后 1 周使用口腔健康影响简表-14(OHIP-14)评估口腔健康相关生活质量(OHRQoL)。通过问卷和视觉模拟量表评估疼痛、社交和工作隔离、外貌、进食和说话能力、饮食变化、睡眠障碍以及 1 周和 1 个月后的不适来评估恢复情况。平均值差异用 95%置信区间(CI)表示。估计 OHRQoL 与恢复之间的关联。p 值<0.05 被认为具有统计学意义。

结果

与 MSFA 相比,上颌窦膜提升术疼痛天数减少 2.1 天(p=0.03,95%CI:0.2-4.1),病假天数减少 1.2 天(p=0.01,95%CI:0.3-2.1)。在进食和说话能力、外貌、工作表现和睡眠障碍方面没有显著差异。受损的 OHRQoL 与恢复之间没有显著关联。女性的 OHIP-14 评分比男性高 4.77(p=0.01,95%CI:1.60-7.94),而年龄与 OHIP-14 之间的关联为-0.10(p=0.28,95%CI:-0.28 至 0.08)。

结论

与 MSFA 相比,上颌窦膜提升术疼痛天数和病假天数明显减少。自体骨移植的采集似乎对上颌窦底提升后恢复的感知有显著影响。

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