From the Department of Infectious Disease and Department of Cardiology, University of Virginia Children's Hospital, Charlottesville, Virginia.
Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.
Pediatr Infect Dis J. 2022 Feb 1;41(2):145-147. doi: 10.1097/INF.0000000000003335.
Immune reconstitution inflammatory syndrome can be a complication of cryptococcal meningitis after immune reconstitution from antiretroviral therapy in HIV or reduced immune suppression in transplant recipients. In this case report, the authors discuss the diagnosis and management of cryptococcal-associated immune reconstitution inflammatory syndrome in a 10-year-old pediatric heart transplant recipient.
免疫重建炎症综合征可能是 HIV 患者接受抗反转录病毒治疗后免疫重建或移植受者免疫抑制减少时发生隐球菌性脑膜炎的并发症。本病例报告讨论了一名 10 岁儿科心脏移植受者中隐球菌相关免疫重建炎症综合征的诊断和治疗。