一项针对乳腺癌和前列腺癌幸存者的基于互联网的混合式体育活动试验中参与者和非参与者的特征：横断面研究

Characteristics of Participants and Nonparticipants in a Blended Internet-Based Physical Activity Trial for Breast and Prostate Cancer Survivors: Cross-sectional Study.

作者信息

Vd Wiel Hester J, Stuiver Martijn M, May Anne M, van Grinsven Susan, Benink Marlou F A, Aaronson Neil K, Oldenburg Hester S A, van der Poel Henk G, van Harten Wim H, Groen Wim G

机构信息

Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, Netherlands.

Center for Quality of Life, Netherlands Cancer Institute, Amsterdam, Netherlands.

出版信息

JMIR Cancer. 2021 Oct 5;7(4):e25464. doi: 10.2196/25464.

DOI:10.2196/25464

PMID:34609311

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8527379/

Abstract

BACKGROUND

As the number of cancer survivors is increasing, it is important to be able to offer exercise and physical activity (PA)-promoting interventions that are both effective and reasonably accessible. Internet-based interventions are typically less expensive and more accessible alternatives to on-site supervised interventions. Currently, little is known about the characteristics of nonparticipants in PA promotion trials in the cancer survivorship setting, both in general and specifically in trials using internet-supported interventions.

OBJECTIVE

This study aims to gain insight into the characteristics associated with nonparticipation in a blended internet-based supported intervention trial to promote PA.

METHODS

Breast and prostate cancer survivors, 3-36 months after primary curative treatment, were invited to participate in the PABLO trial; this trial compared an internet-based intervention to enhance PA levels, with or without additional support from a physical therapist, to usual care. Participants and nonparticipants were asked to complete a comprehensive questionnaire assessing sociodemographics, fatigue, and health-related quality of life. Baseline data for participants and nonparticipants were compared using the independent Student t test and chi-square test.

RESULTS

The inclusion rate in the trial was 11.03% (137/1242). Of the nonparticipants, 13.95% (154/1104) completed the questionnaire. Participants were more highly educated (P=.04), had a paid job less often (P=.03), and were on sick leave more often (P=.03). They reported less PA per week, both moderate (P=.03) and vigorous (P<.01), before diagnosis and during leisure time (P<.01, effect size [ES]=0.44). They reported a significantly lower stage of change (P≤.01), lower self-efficacy (P<.01, ES=0.61), perceived barriers to PA (P<.01, ES=0.54), and more general fatigue (P<.01, ES=0.60). Participants reported lower health-related quality of life for most domains (ES ranging from 0.34 for mental health to 0.48 for social functioning). No significant differences were found for other sociodemographics, mood state, or attitudes toward or perceived social support for PA.

CONCLUSIONS

The participants who self-selected for trial participation reported lower PA levels before diagnosis and a stronger need for support compared with nonparticipants. The trial thus included those patients who might benefit the most from internet-based supportive PA interventions.

TRIAL REGISTRATION

Netherlands trial register NTR6911; https://www.trialregister.nl/trial/6733.

摘要

背景

随着癌症幸存者数量的增加，提供有效且可合理获取的促进运动和身体活动（PA）的干预措施至关重要。基于互联网的干预通常比现场监督干预成本更低且更易获取。目前，对于癌症幸存者环境中PA促进试验的非参与者特征，总体情况以及特别是使用互联网支持干预的试验中的情况，了解甚少。

目的

本研究旨在深入了解与不参与基于互联网的混合支持干预试验以促进PA相关的特征。

方法

邀请原发性根治性治疗后3至36个月的乳腺癌和前列腺癌幸存者参与PABLO试验；该试验将一种旨在提高PA水平的基于互联网的干预措施（有或没有物理治疗师的额外支持）与常规护理进行比较。参与者和非参与者被要求完成一份综合问卷，评估社会人口统计学、疲劳和健康相关生活质量。使用独立样本t检验和卡方检验比较参与者和非参与者的基线数据。

结果

试验纳入率为11.03%（137/1242）。在非参与者中，13.95%（154/1104）完成了问卷。参与者受教育程度更高（P = 0.04），有带薪工作的频率更低（P = 0.03），休病假的频率更高（P = 0.03）。他们报告在诊断前和休闲时间每周的PA量更少，包括中度（P = 0.03）和剧烈（P < 0.01）PA。他们报告的行为改变阶段显著更低（P≤0.01），自我效能更低（P < 0.01，效应量[ES]=0.61），PA的感知障碍更低（P < 0.01，ES = 0.54）以及更普遍的疲劳（P < 0.01，ES = 0.60）。参与者在大多数领域报告的健康相关生活质量更低（ES范围从心理健康的0.34到社会功能的0.48）。在其他社会人口统计学、情绪状态或对PA的态度或感知社会支持方面未发现显著差异。