Department of Thoracic Surgery, Kumamoto University Hospital, 1-1-1 Honjo, Chuo-ku, Kumamoto, Japan.
Cardiovascular Surgery, Kumamoto University Hospital, 1-1-1 Honjo, Chuo-ku, Kumamoto, Japan.
J Med Case Rep. 2021 Oct 6;15(1):491. doi: 10.1186/s13256-021-03091-y.
Cardiac myxoma is the most common type of primary cardiac tumor, and thymic carcinoid is a rare neuroendocrine tumor. No previous reports have described surgical management of concomitant occurrence of these neoplasms. We report a case of simultaneous surgical resection in a patient with coexisting cardiac myxoma and atypical thymic carcinoid.
A 44-year-old Japanese woman underwent chest roentgenography revealing an abnormality in the mediastinum. Computed tomography revealed a 100 mm mass in the anterior mediastinum and also a 30 mm mass in the left atrium. The mediastinal tumor was diagnosed as atypical carcinoid by biopsy. Having completed resection of atypical thymic carcinoid, cardiac mass was successfully resected with careful consideration of minimizing operation time and optimizing patient safety and oncological treatment. The histopathological diagnosis of the cardiac mass was myxoma. No adjuvant chemotherapy was administered, and no recurrence was seen as of the 45 month follow-up.
The simultaneous surgery of cardiac myxoma and atypical thymic carcinoid was feasible and effective. To the best of our knowledge, this is the first case report to describe one-stage treatment of these neoplasms.
心脏黏液瘤是最常见的原发性心脏肿瘤，胸腺癌是一种罕见的神经内分泌肿瘤。以前没有报道描述同时发生这些肿瘤的手术治疗。我们报告了一例同时发生心脏黏液瘤和非典型胸腺癌的患者的手术切除。
一名 44 岁的日本女性因胸部 X 线检查显示纵隔异常而就诊。计算机断层扫描显示前纵隔有一个 100 毫米的肿块，左心房也有一个 30 毫米的肿块。纵隔肿瘤通过活检诊断为非典型类癌。在仔细考虑将手术时间最小化、优化患者安全性和肿瘤治疗的前提下，成功切除了非典型胸腺类癌。心脏肿块的组织病理学诊断为黏液瘤。未进行辅助化疗，随访 45 个月未见复发。
心脏黏液瘤和非典型胸腺癌的同期手术是可行和有效的。据我们所知，这是首例描述这些肿瘤一期治疗的病例报告。
