Appl Opt. 2021 Aug 1;60(22):6593-6599. doi: 10.1364/AO.428785.
Static scattering is detrimental to the accuracy of laser speckle contrast analysis (LASCA) measurements on skin when, instead of percentile change monitoring, absolute perfusion values are needed, e.g., for tissue injury examination. Perfusion values were calculated using two evaluation models, while changing the dynamic/static scattering ratio of monitored skin and tissue phantoms. Results were strongly affected by the significant increase of static contribution. Measurements on a modified tissue phantom showed that the changes in the measured perfusion values were mostly caused by the mixed scattering, which was omitted by the tested models. Dynamic ratio values obtained by multi-exposure LASCA could be used for perfusion data correction.
当需要绝对灌注值（例如用于组织损伤检查）而不是百分比变化监测时，静态散射会对皮肤的激光散斑对比分析（LASCA）测量的准确性造成损害。通过改变监测皮肤和组织模型的动态/静态散射比，使用两种评估模型来计算灌注值。结果受到静态贡献显著增加的强烈影响。在改进的组织模型上的测量表明，测量的灌注值的变化主要是由测试模型忽略的混合散射引起的。通过多曝光 LASCA 获得的动态比值可用于灌注数据校正。
