Division of Hospital MedicineUniversity of California, San Francisco, San Francisco, California.
Division of Hospital Medicine, Priscilla Chan and Mark Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, California.
J Hosp Med. 2021 Oct;16(10):589-595. doi: 10.12788/jhm.3667.
Differential opioid prescribing patterns have been reported in non-White patient populations. However, these disparities have not been well described among hospitalized medical inpatients.
To describe differences in opioid prescribing patterns among inpatients discharged from the general medicine service based on race/ethnicity.
DESIGN, SETTING, AND PARTICIPANTS: For this retrospective study, we performed a multivariable logistic regression for patient race/ethnicity and whether patients received an opioid prescription at discharge and a negative binomial regression for days of opioids prescribed at discharge. The study included all 10,953 inpatients discharged from the general medicine service from June 2012 to November 2018 at University of California San Francisco Medical Center who received opioids during the last 24 hours of their hospitalization.
We examined two primary outcomes: whether a patient received an opioid prescription at discharge, and, for patients prescribed opioids, the number of days dispensed.
Compared with White patients, Black patients were less likely to receive an opioid prescription at discharge (predicted population rate of 47.6% vs 50.7%; average marginal effect [AME], -3.1%; 95% CI, -5.5% to -0.8%). Asian patients were more likely to receive an opioid prescription on discharge (predicted population rate, 55.6% vs 50.7%; AME, +4.9; 95% CI, 1.5%-8.3%). We also found that Black patients received a shorter duration of opioid days compared with White patients (predicted days of opioids on discharge, 15.7 days vs 17.8 days; AME, -2.1 days; 95% CI, -3.3 to -0.9).
Black patients were less likely to receive opioids and received shorter courses at discharge compared with White patients, adjusting for covariates. Asian patients were the most likely to receive an opioid prescription.
在非白人群体中,已经报道了不同的阿片类药物处方模式。然而,这些差异在住院内科患者中并没有得到很好的描述。
根据种族/民族描述从普通内科出院的住院患者阿片类药物处方模式的差异。
设计、地点和参与者:在这项回顾性研究中,我们对患者的种族/民族与患者是否在出院时收到阿片类药物处方进行了多变量逻辑回归分析,对出院时开出的阿片类药物天数进行了负二项回归分析。研究包括 2012 年 6 月至 2018 年 11 月期间在加利福尼亚大学旧金山医疗中心普通内科出院的所有 10953 名接受住院期间最后 24 小时内使用过阿片类药物的患者。
我们检查了两个主要结局:患者是否在出院时收到阿片类药物处方,以及为开出阿片类药物的患者开出的阿片类药物天数。
与白人患者相比,黑人患者出院时接受阿片类药物处方的可能性较小(预测人群的接受率为 47.6%比 50.7%;平均边缘效应[AME],-3.1%;95%置信区间,-5.5%至-0.8%)。亚洲患者出院时更有可能接受阿片类药物处方(预测人口接受率,55.6%比 50.7%;AME,+4.9%;95%置信区间,1.5%-8.3%)。我们还发现,与白人患者相比,黑人患者接受的阿片类药物天数较短(出院时预计的阿片类药物天数为 15.7 天比 17.8 天;AME,-2.1 天;95%置信区间,-3.3 至-0.9)。
在调整了协变量后,与白人患者相比,黑人患者接受阿片类药物的可能性较小,出院时接受的疗程也较短。亚洲患者最有可能收到阿片类药物处方。