Department of Biotechnology, Thapar Institute of Engineering & Technology (Deemed to be University), Patiala, 147001, Punjab, India.
Department of Agriculture and Environmental Sciences, National Institute of Food Technology Entrepreneurship and Management, Kundli, Sonepat-131028, Haryana, India.
Nanotechnology. 2021 Oct 22;33(2). doi: 10.1088/1361-6528/ac2d4c.
Insecticide cartap hydrochloride (C) was fabricated as nanospheres by a two-step method of ionic gelification and polyelectrolyte complexation of alginate (ALG) and chitosan (CS) to undermine its adverse effects on environment. Nanospheres were characterized by field emission scanning electron microscope, Fourier transform infrared spectra and x-ray diffraction. The size of cartap hydrochloride entrapped chitosan alginate nanospheres (C-CS-ALG nps) was in range of 107.58-173.07 nm. Cartap hydrochloride nanospheres showed encapsulation efficiency of 76.19% and were stable for 30 d at ambient temperature. Release of cartap from nanospheres fitted best with first order linear kinetics followed by Hixson and Higuchi model suggesting super case II transport release. With the application of such control release nanoformulations, it is possible to reduce the frequency of field application of insecticide due to its slow release to the target organism, which is economical as well as environmentally safe.
杀虫剂 cartap 盐酸盐（C）通过离子凝胶化和海藻酸钠（ALG）与壳聚糖（CS）的聚电解质络合的两步法制备为纳米球，以减少其对环境的不利影响。纳米球通过场发射扫描电子显微镜、傅里叶变换红外光谱和 X 射线衍射进行了表征。包埋 cartap 盐酸盐的壳聚糖海藻酸钠纳米球（C-CS-ALG nps）的尺寸在 107.58-173.07nm 范围内。cartap 盐酸盐纳米球的包封效率为 76.19%，在环境温度下稳定 30d。纳米球中 cartap 的释放最符合一级线性动力学，其次是 Hixson 和 Higuchi 模型，表明超二级运输释放。通过应用这种控制释放纳米制剂，可以减少由于其向靶标生物的缓慢释放而导致的杀虫剂田间施用量的频率，这在经济上和环境上都是安全的。
