Division of Urology, Department of Surgery, Linkou Chang Gung Memorial Hospital, Taoyuan City, 33302, Taiwan.
College of Medicine, Chang Gung University, Taoyuan City, 33302, Taiwan.
Clin Interv Aging. 2021 Sep 29;16:1747-1756. doi: 10.2147/CIA.S329468. eCollection 2021.
Transurethral procedures, including transurethral resection of the prostate (TURP) and laser prostatectomy, are often linked to emergency room (ER) visits for postoperative bleeding. Although some studies have been conducted, the risk factors associated with these ER visits are not completely understood. This retrospective cohort study identified potential risk factors associated with ER visits for postoperative bleeding.
Preoperative assessment data and operational and postoperational parameters recorded at Chang Gung Memorial Hospital, Taiwan between December 2015 and January 2017 for patients who underwent elective transurethral procedures were analyzed to identify potential risk factors. The primary endpoint was ER visits for gross hematuria within three months following operation, and the secondary endpoint was ER visits for blood clot-induced urinary retention (clot retention) within three months following operation.
A total of 665 patients who underwent elective transurethral procedures were enrolled. The transurethral procedures included monopolar transurethral resection of the prostate (M-TURP), bipolar TURP (B-TURP), greenlight photoselective vaporization of the prostate (PVP), thulium laser enucleation of the prostate (ThuLEP) and thulium laser transurethral vaporesection of the prostate (ThuVARP). Regarding ER visits for clot retention within three months, multivariable logistic regression revealed significantly lower rates of clot retention in patients who received B-TURP than in those who underwent ThuVARP (AOR, 0.18; 95% confidence interval [CI], 0.04-0.82, p = 0.027). Moreover, significantly higher clot retention was observed in patients who underwent two or more rounds of manual irrigation (AOR, 9.51; 95% CI, 1.66-54.43, p = 0.011).
Multiple manual irrigations shortly after operation can be considered a novel predictor of postoperative clot retention-related ER visits. Among the transurethral procedures, ThuVARP was associated with a higher risk of clot retention-related ER visits than was B-TURP.
经尿道手术,包括经尿道前列腺切除术(TURP)和激光前列腺切除术,常与术后出血相关的急诊室(ER)就诊有关。尽管已经进行了一些研究,但与这些 ER 就诊相关的风险因素仍不完全清楚。这项回顾性队列研究确定了与术后出血相关的 ER 就诊的潜在风险因素。
分析了台湾长庚纪念医院 2015 年 12 月至 2017 年 1 月期间接受选择性经尿道手术的患者的术前评估数据以及手术操作和术后参数,以确定潜在的风险因素。主要终点是术后三个月内因肉眼血尿而到 ER 就诊,次要终点是术后三个月内因血凝块引起的尿潴留(血块潴留)而到 ER 就诊。
共纳入 665 例接受选择性经尿道手术的患者。经尿道手术包括单极经尿道前列腺切除术(M-TURP)、双极 TURP(B-TURP)、绿光前列腺选择性汽化术(PVP)、钬激光前列腺剜除术(ThuLEP)和钬激光经尿道前列腺汽化切除术(ThuVARP)。关于术后三个月内因血块潴留而到 ER 就诊的情况,多变量逻辑回归显示,接受 B-TURP 的患者发生血块潴留的比例明显低于接受 ThuVARP 的患者(AOR,0.18;95%置信区间[CI],0.04-0.82,p=0.027)。此外,接受两次或更多次手动冲洗的患者发生血块潴留的比例明显更高(AOR,9.51;95%CI,1.66-54.43,p=0.011)。
术后短期内多次手动冲洗可被视为术后与血块潴留相关的 ER 就诊的新预测因素。在经尿道手术中,与 B-TURP 相比,ThuVARP 与血块潴留相关的 ER 就诊风险更高。